Molecular biology of pseudorabies virus: impact on neurovirology and veterinary medicine

LE Pomeranz, AE Reynolds… - … and molecular biology …, 2005 - journals.asm.org
Pseudorabies virus (PRV) is a herpesvirus of swine, a member of the Alphaherpesvirinae
subfamily, and the etiological agent of Aujeszky's disease. This review describes the …

HeLa cells 50 years on: the good, the bad and the ugly

JR Masters - Nature Reviews Cancer, 2002 - nature.com
HeLa cells—the first continuous cancer cell line—have been a mainstay of cancer research
ever since their isolation from the aggressive glandular cervical cancer of a young woman …

Herpes simplex virus type 1 and bovine herpesvirus 1 latency

C Jones - Clinical microbiology reviews, 2003 - journals.asm.org
Primary infection by herpes simplex virus type 1 (HSV-1) can cause clinical symptoms in the
peripheral and central nervous system, upper respiratory tract, and gastrointestinal tract …

Ultrastructural Localization of the Herpes Simplex Virus Type 1 UL31, UL34, and US3 Proteins Suggests Specific Roles in Primary Envelopment and Egress of …

AE Reynolds, EG Wills, RJ Roller, BJ Ryckman… - Journal of …, 2002 - journals.asm.org
The wild-type UL31, UL34, and US3 proteins localized on nuclear membranes and
perinuclear virions; the US3 protein was also on cytoplasmic membranes and extranuclear …

Plus-and minus-end directed microtubule motors bind simultaneously to herpes simplex virus capsids using different inner tegument structures

K Radtke, D Kieneke, A Wolfstein, K Michael… - PLoS …, 2010 - journals.plos.org
Many viruses depend on host microtubule motors to reach their destined intracellular
location. Viral particles of neurotropic alphaherpesviruses such as herpes simplex virus 1 …

Recombinant baculoviruses as mammalian cell gene-delivery vectors

TA Kost, JP Condreay - Trends in biotechnology, 2002 - cell.com
The baculovirus expression system has been used extensively for the expression of
recombinant proteins in insect cells. Recently, recombinant baculovirus vectors engineered …

Towards an understanding of the herpes simplex virus type 1 latency‐reactivation cycle

GC Perng, C Jones - Interdisciplinary perspectives on infectious …, 2010 - Wiley Online Library
Infection by herpes simplex virus type 1 (HSV‐1) can cause clinical symptoms in the
peripheral and central nervous system. Recurrent ocular shedding can lead to corneal …

Herpes simplex virus type 1 primary envelopment: UL34 protein modification and the US3-UL34 catalytic relationship

BJ Ryckman, RJ Roller - Journal of virology, 2004 - journals.asm.org
The herpes simplex virus type 1 (HSV-1) US3 kinase is likely important for primary
envelopment of progeny nucleocapsids since it localizes to the nuclear envelope of infected …

The suppression of apoptosis by α-herpesvirus

Y You, AC Cheng, MS Wang, RY Jia, KF Sun… - Cell death & …, 2017 - nature.com
Apoptosis, an important innate immune mechanism that eliminates pathogen-infected cells,
is primarily triggered by two signalling pathways: the death receptor pathway and the …

Virus-mediated inactivation of anti-apoptotic Bcl-2 family members promotes Gasdermin-E-dependent pyroptosis in barrier epithelial cells

MH Orzalli, A Prochera, L Payne, A Smith, JA Garlick… - Immunity, 2021 - cell.com
Two sets of innate immune proteins detect pathogens. Pattern recognition receptors (PRRs)
bind microbial products, whereas guard proteins detect virulence factor activities by the …