Multiple sclerosis (MS) is known to be a partially heritable autoimmune disease. The risk of
develo** MS increases from typically 1 in 1,000 in the normal population to 1 in 4 or so for …

Understanding the mechanisms involved in the activation of an immune response is
essential to many fields in human health, including vaccine development and personalized …

Multiple sclerosis (MS) is a complex neurological disorder characterized by an aberrant
immune system that affects patients' quality of life. Several environmental factors have …

T cell receptor (TCR) recognition of antigenic peptides bound and presented by class I major
histocompatibility complex (MHC) proteins underlies the cytotoxic immune response to …

Abstract Epstein–Barr virus and Mycobacterium avium subsp. paratuberculosis (MAP) have
been associated to multiple sclerosis (MS). We searched for antibodies against the …

The interaction between T-cell receptors (TCRs) and major histocompatibility complex
(MHC)-bound epitopes is one of the most important processes in the adaptive human …

Acute encephalitis syndrome outbreak has emerged as a major health concern on both
national and international scales. Brain inflammation/infections caused by Japanese …

Major histocompatibility complex (MHC) class I molecules (proteins) bind peptides of eight to
ten amino acids to present them at the cell surface to cytotoxic T cells. The class I binding …

Microtubule associated serine/threonine kinase (MASTL) is an important Ser/Thr kinase
belonging to the family of AGC kinases. It is the human orthologue of Greatwall kinase (Gwl) …

Risk of the development of multiple sclerosis (MS) is known to be increased in individuals
bearing distinct class II human leukocyte antigen (HLA) variants, whereas some of them may …