Serotonin modulation of prefronto-hippocampal rhythms in health and disease
There is mounting evidence that most cognitive functions depend upon the coordinated
activity of neuronal networks often located far from each other in the brain. Ensembles of …
activity of neuronal networks often located far from each other in the brain. Ensembles of …
Intermediate phenotypes and biomarkers of treatment outcome in major depressive disorder
Major depressive disorder (MDD) is a pleomorphic illness originating from gene x
environment interactions. Patients with differing symptom phenotypes receive the same …
environment interactions. Patients with differing symptom phenotypes receive the same …
Altered resting-state EEG source functional connectivity in schizophrenia: the effect of illness duration
G Di Lorenzo, A Daverio, F Ferrentino… - Frontiers in human …, 2015 - frontiersin.org
Despite the increasing body of evidence supporting the hypothesis of schizophrenia as a
disconnection syndrome, studies of resting-state EEG Source Functional Connectivity (EEG …
disconnection syndrome, studies of resting-state EEG Source Functional Connectivity (EEG …
[HTML][HTML] Opportunities for multiscale computational modelling of serotonergic drug effects in Alzheimer's disease
Alzheimer's disease (AD) is an age-specific neurodegenerative disease that compromises
cognitive functioning and impacts the quality of life of an individual. Pathologically, AD is …
cognitive functioning and impacts the quality of life of an individual. Pathologically, AD is …
Toward a multiscale modeling framework for understanding serotonergic function
Despite its importance in regulating emotion and mental wellbeing, the complex structure
and function of the serotonergic system present formidable challenges toward …
and function of the serotonergic system present formidable challenges toward …
[HTML][HTML] Neonatal hypoxia impairs serotonin release and cognitive functions in adult mice
KKY Lee, B Chattopadhyaya, ASF do Nascimento… - Neurobiology of …, 2024 - Elsevier
Children who experienced moderate perinatal asphyxia (MPA) are at risk of develo** long
lasting subtle cognitive and behavioral deficits, including learning disabilities and emotional …
lasting subtle cognitive and behavioral deficits, including learning disabilities and emotional …
Unveiling serotonergic dysfunction of obsessive-compulsive disorder on prefrontal network dynamics: a computational perspective
L Yin, Y Yu, F Han, Q Wang - Cerebral Cortex, 2024 - academic.oup.com
Abstract Serotonin (5-HT) regulates working memory within the prefrontal cortex network,
which is crucial for understanding obsessive-compulsive disorder. However, the …
which is crucial for understanding obsessive-compulsive disorder. However, the …
An integrated modelling framework for neural circuits with multiple neuromodulators
A Joshi, V Youssofzadeh, V Vemana… - Journal of the …, 2017 - royalsocietypublishing.org
Neuromodulators are endogenous neurochemicals that regulate biophysical and
biochemical processes, which control brain function and behaviour, and are often the targets …
biochemical processes, which control brain function and behaviour, and are often the targets …
Neuropharmacology of altered brain oscillations in schizophrenia
M Koch, C Schmiedt-Fehr, B Mathes - International Journal of …, 2016 - Elsevier
Impairments in spatial and temporal integration of brain network activity are a core feature of
schizophrenia. Neural network oscillatory activity is considered to be fundamentally …
schizophrenia. Neural network oscillatory activity is considered to be fundamentally …
Integrated dopaminergic neuronal model with reduced intracellular processes and inhibitory autoreceptors
M Cullen, KF Wong‐Lin - IET Systems Biology, 2015 - Wiley Online Library
Dopamine (DA) is an important neurotransmitter for multiple brain functions, and
dysfunctions of the dopaminergic system are implicated in neurological and …
dysfunctions of the dopaminergic system are implicated in neurological and …