Abnormalities of intrinsic regional brain activity in first-episode and chronic schizophrenia: a meta-analysis of resting-state functional MRI

J Gong, J Wang, X Luo, G Chen, H Huang… - Journal of psychiatry and …, 2020 - jpn.ca
Background: Resting-state functional MRI (fMRI) studies have provided much evidence for
abnormal intrinsic brain activity in schizophrenia, but results have been inconsistent …

Structural and functional brain abnormalities in schizophrenia: a cross-sectional study at different stages of the disease

C Zhao, J Zhu, X Liu, C Pu, Y Lai, L Chen, X Yu… - Progress in Neuro …, 2018 - Elsevier
Structural and functional deficits associated with schizophrenia are observed prior to the
onset of psychosis and differ according to the stage of illness. However, most previous …

Altered resting-state brain activity in schizophrenia and obsessive-compulsive disorder compared with non-psychiatric controls: commonalities and distinctions across …

Y Zhang, J Liao, Q Li, X Zhang, L Liu, J Yan… - Frontiers in …, 2021 - frontiersin.org
Backgrounds: Schizophrenia (SCZ) and obsessive-compulsive disorder (OCD) are
classified as two chronic psychiatric disorders with high comorbidity rate and shared clinical …

Altered patterns of the fractional amplitude of low-frequency fluctuation and functional connectivity between deficit and non-deficit schizophrenia

C Zhou, X Tang, W You, X Wang, X Zhang… - Frontiers in …, 2019 - frontiersin.org
Objective: A limited number of studies have previously reported on the regional activity
[amplitude of low-frequency fluctuation (ALFF)] and functional integration [functional …

Modality-dependent impact of hallucinations on low-frequency fluctuations in schizophrenia

SM Hare, JM Ford, A Ahmadi, E Damaraju… - Schizophrenia …, 2017 - academic.oup.com
Prior resting-state functional magnetic resonance imaging (fMRI) analyses have identified
patterns of functional connectivity associated with hallucinations in schizophrenia (Sz). In …

Modulation of hippocampal activity in schizophrenia with levetiracetam: a randomized, double-blind, cross-over, placebo-controlled trial

MJ Roeske, M McHugo, B Rogers… - …, 2024 - nature.com
Hippocampal hyperactivity is a novel pharmacological target in the treatment of
schizophrenia. We hypothesized that levetiracetam (LEV), a drug binding to the synaptic …

Default mode network aberrant connectivity associated with neurological soft signs in schizophrenia patients and unaffected relatives

L Galindo, D Bergé, GK Murray, A Mané… - Frontiers in …, 2018 - frontiersin.org
Brain connectivity and neurological soft signs (NSS) are reportedly abnormal in
schizophrenia and unaffected relatives, suggesting they might be useful neurobiological …

Aberrant intra‐and internetwork functional connectivity patterns of the anterior and posterior hippocampal networks in schizophrenia

XW Li, H Liu, YY Deng, ZY Li, YH Jiang… - CNS Neuroscience & …, 2023 - Wiley Online Library
Aim Schizophrenia is associated with abnormal hippocampal structure and function.
Available evidence suggests that the anterior and posterior hippocampus are differentially …

Reduced GluN1 in mouse dentate gyrus is associated with CA3 hyperactivity and psychosis-like behaviors

A Segev, M Yanagi, D Scott, SA Southcott… - Molecular …, 2020 - nature.com
Recent findings from in vivo-imaging and human post-mortem tissue studies in
schizophrenic psychosis (SzP), have demonstrated functional and molecular changes in …

Association between NRGN gene polymorphism and resting-state hippocampal functional connectivity in schizophrenia

Y Zhang, X Gong, Z Yin, L Cui, J Yang, P Wang, Y Zhou… - BMC psychiatry, 2019 - Springer
Background Based on genome-wide association studies, a single-nucleotide polymorphism
in the NRGN gene (rs12807809) is considered associated with schizophrenia (SZ) …