Dietary fibre has long been established as a nutritionally important, health-promoting food
ingredient. Modern dietary practices have seen a significant reduction in fibre consumption …

A substantial body of literature has provided evidence for the role of gut microbiota in
metabolic diseases including type 2 diabetes. However, reports vary regarding the …

A strong and expanding evidence base supports the influence of gut microbiota in human
metabolism. Altered glucose homeostasis is associated with altered gut microbiota, and is …

Abstract Objective (Background): Alzheimer's disease (AD), clinically characterized by the
progressive neurodegenerative condition and cognitive impairment, is one of the main …

Objective Tryptophan can be catabolised to various metabolites through host kynurenine
and microbial indole pathways. We aimed to examine relationships of host and microbial …

Diabetic kidney disease (DKD) is a progressive disorder, which is increasing globally in
prevalence due to the increased incidence of obesity and diabetes mellitus. Despite optimal …

Type 2 diabetes mellitus (T2DM) is a common clinical chronic disease, while its
pathogenesis is still inconclusive. Intestinal flora, the largest micro-ecological system in the …

The genus Roseburia consists of obligate Gram-positive anaerobic bacteria that are slightly
curved, rod-shaped and motile by means of multiple subterminal flagella. It includes five …

Berberine is a natural pentacyclic isoquinoline alkaloid that has been isolated as the
principal component of many popular medicinal plants such as the genus Berberis, Coptis …

The intestinal microbiota has increasingly been shown to have a vital role in various aspects
of human health. Indeed, several studies have linked alterations in the gut microbiota with …