Higher mortality of COVID-19 in males: sex differences in immune response and cardiovascular comorbidities
LA Bienvenu, J Noonan, X Wang… - Cardiovascular …, 2020 - academic.oup.com
The high mortality rate of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
infection is a critical concern of the coronavirus disease 2019 (COVID-19) pandemic …
infection is a critical concern of the coronavirus disease 2019 (COVID-19) pandemic …
[PDF][PDF] Oxidative stress and inflammatory markers in prediabetes and diabetes.
K Luc, A Schramm-Luc, TJ Guzik… - Journal of Physiology & …, 2019 - researchgate.net
Prediabetes is a state of elevated plasma glucose in which the threshold for diabetes has
not yet been reached and can predispose to the development of type 2 diabetes and …
not yet been reached and can predispose to the development of type 2 diabetes and …
Role of inflammation, immunity, and oxidative stress in hypertension: New insights and potential therapeutic targets
Z Zhang, L Zhao, X Zhou, X Meng, X Zhou - Frontiers in immunology, 2023 - frontiersin.org
Hypertension is regarded as the most prominent risk factor for cardiovascular diseases,
which have become a primary cause of death, and recent research has demonstrated that …
which have become a primary cause of death, and recent research has demonstrated that …
Targeting the NLRP3 inflammasome in cardiovascular diseases
The NACHT, leucine-rich repeat (LRR), and pyrin domain (PYD)-containing protein 3
(NLRP3) inflammasome is an intracellular sensing protein complex that plays a major role in …
(NLRP3) inflammasome is an intracellular sensing protein complex that plays a major role in …
Immune mechanisms of hypertension
Hypertension affects 30% of adults and is the leading risk factor for heart attack and stroke.
Traditionally, hypertension has been regarded as a disorder of two systems that are involved …
Traditionally, hypertension has been regarded as a disorder of two systems that are involved …
Hypertension: do inflammation and immunity hold the key to solving this epidemic?
Elevated cardiovascular risk including stroke, heart failure, and heart attack is present even
after normalization of blood pressure in patients with hypertension. Underlying immune cell …
after normalization of blood pressure in patients with hypertension. Underlying immune cell …
Inflammasomes and pyroptosis as therapeutic targets for COVID-19
The inflammatory response to severe acute respiratory syndrome–related coronavirus 2
infection has a direct impact on the clinical outcomes of coronavirus disease 2019 patients …
infection has a direct impact on the clinical outcomes of coronavirus disease 2019 patients …
Gasdermins and pyroptosis in the kidney
EE Elias, B Lyons, DA Muruve - Nature Reviews Nephrology, 2023 - nature.com
Pyroptosis is a form of regulated cell death that is mediated by the membrane-targeting, pore-
forming gasdermin family of proteins. Pyroptosis was initially described as a caspase 1-and …
forming gasdermin family of proteins. Pyroptosis was initially described as a caspase 1-and …
Pathophysiology of cardiovascular diseases: new insights into molecular mechanisms of atherosclerosis, arterial hypertension, and coronary artery disease
W Frąk, A Wojtasińska, W Lisińska, E Młynarska… - Biomedicines, 2022 - mdpi.com
Cardiovascular diseases (CVDs) are disorders associated with the heart and circulatory
system. Atherosclerosis is its major underlying cause. CVDs are chronic and can remain …
system. Atherosclerosis is its major underlying cause. CVDs are chronic and can remain …
Hypertension and COVID-19: current evidence and perspectives
Abstract Coronavirus disease 2019 (COVID-19) outbreak, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), represents a real challenge for health …
respiratory syndrome coronavirus 2 (SARS-CoV-2), represents a real challenge for health …