Enzymes, In Vivo Biocatalysis, and Metabolic Engineering for Enabling a Circular Economy and Sustainability

P Intasian, K Prakinee, A Phintha, D Trisrivirat… - Chemical …, 2021 - ACS Publications
Since the industrial revolution, the rapid growth and development of global industries have
depended largely upon the utilization of coal-derived chemicals, and more recently, the …

[HTML][HTML] Recent trends in methane to bioproduct conversion by methanotrophs

A Gęsicka, P Oleskowicz-Popiel, M Łężyk - Biotechnology advances, 2021 - Elsevier
Methane is an abundant and low-cost gas with high global warming potential and its use as
a feedstock can help mitigate climate change. Variety of valuable products can be produced …

Methanotrophs: Metabolic versatility from utilization of methane to multi-carbon sources and perspectives on current and future applications

HTQ Le, EY Lee - Bioresource Technology, 2023 - Elsevier
The development of biorefineries for a sustainable bioeconomy has been driven by the
concept of utilizing environmentally friendly and cost-effective renewable energy sources …

Engineered methanotrophy: a sustainable solution for methane-based industrial biomanufacturing

AD Nguyen, EY Lee - Trends in Biotechnology, 2021 - cell.com
Methane is a promising feedstock with high abundance and low cost for the sustainable
production of biochemicals and biofuels. Methanotrophic bacteria are particularly interesting …

C1-based biomanufacturing: Advances, challenges and perspectives

X Lv, W Yu, C Zhang, P Ning, J Li, Y Liu, G Du… - Bioresource …, 2023 - Elsevier
Abstract One-carbon (C1) compounds have emerged as a key research focus due to the
growth of metabolic engineering and synthetic biology as affordable and sustainable …

Outlook on engineering methylotrophs for one-carbon-based industrial biotechnology

DN Pham, AD Nguyen, EY Lee - Chemical Engineering Journal, 2022 - Elsevier
Methane and carbon dioxide (CO 2) account for the most abundant greenhouse gases
(GHGs). The removal of atmospheric methane and CO 2 is an urgent mission contributing to …

Bioconversion of methane to cadaverine and lysine using an engineered type II methanotroph, Methylosinus trichosporium OB3b

TT Nguyen, OK Lee, S Naizabekov, EY Lee - Green Chemistry, 2020 - pubs.rsc.org
Methane is an attractive low-priced feedstock used for the biotechnological production of
value-added products. We developed a metabolically engineered strain of a type II …

Methanotrophs as a reservoir for bioactive secondary metabolites: Pitfalls, insights and promises

UM Vasudevan, DHA Mai, S Krishna, EY Lee - Biotechnology Advances, 2023 - Elsevier
Methanotrophs are potent natural producers of several bioactive secondary metabolites
(SMs) including isoprenoids, polymers, peptides, and vitamins. Cryptic biosynthetic gene …

Unlocking the biosynthesis of sesquiterpenoids from methane via the methylerythritol phosphate pathway in methanotrophic bacteria, using α-humulene as a model …

AD Nguyen, D Kim, EY Lee - Metabolic Engineering, 2020 - Elsevier
Isoprenoids are an abundant and diverse class of natural products with various applications
in the pharmaceutical, cosmetics and biofuel industries. A methanotroph-based biorefinery …

A De Novo Auto‐Activated Solar‐Driven Biohybrid System for Hydrogen Production in Methanotrophic Cells

Z Jiao, G Li, S Guo, W Wang, Q Hou, Y Li… - Angewandte …, 2025 - Wiley Online Library
Climate change driving by greenhouse gas emissions from petroleum‐based energy has
garnered significant attention. Renewable energy production via a sustainable system that …