Recent advances in DNA gyrase-targeted antimicrobial agents

SN Dighe, TA Collet - European Journal of Medicinal Chemistry, 2020 - Elsevier
Antimicrobial resistance is one of the greatest challenges facing the world today. In the
United States alone, it is responsible for the death of more than 20,000 people each year …

Recent developments of target based coumarin derivatives as potential anticancer agents

NS Goud, P Kumar, RD Bharath - Mini reviews in medicinal …, 2020 - benthamdirect.com
Cancer is the second life-threatening disease worldwide, and it resulted in around 9.6
million deaths globally in 2018. The multidrug-resistant cancers and non-selectivity create …

Synthesis, biofilm formation inhibitory, and inflammation inhibitory activities of new coumarin derivatives

GE Ahmed, ZA Elshahid, ER El-Sawy… - Scientific Reports, 2024 - nature.com
Coumarins are heterocycles of great interest in the development of valuable active
structures in chemistry and biological domains. The ability of coumarins to inhibit biofilm …

A new coumarin compound DCH combats methicillin-resistant Staphylococcus aureus biofilm by targeting arginine repressor

D Qu, Z Hou, J Li, L Luo, S Su, Z Ye, Y Bai, X Zhang… - Science …, 2020 - science.org
Staphylococcus aureus infection is difficult to eradicate because of biofilm formation and
antibiotic resistance. The increasing prevalence of methicillin-resistant Staphylococcus …

Psidium guajava L. and Psidium brownianum Mart ex DC.: Chemical composition and anti–Candida effect in association with fluconazole

MFB Morais-Braga, DL Sales, JNP Carneiro… - Microbial …, 2016 - Elsevier
The therapeutic combinations have been increasingly used against fungal resistance.
Natural products have been evaluated in combination with pharmaceutical drugs in the …

An efficient synthesis of bisenols in water extract of waste onion peel ash

PW Chia, BS Lim, FSJ Yong, SC Poh… - Environmental Chemistry …, 2018 - Springer
Bisenols and its derivatives are attractive heterocyclic compounds exhibiting a wide range of
biological properties, including anticancer, antipyretic and antimicrobial characteristics …

An insight into the synthesis and SAR of 2, 4-Thiazolidinediones (2, 4-TZD) as Multifunctional scaffold: A review

NS Sethi, DN Prasad, RK Singh - Mini Reviews in Medicinal …, 2020 - ingentaconnect.com
2, 4-Thiazolidinedione (2, 4-TZD) is a versatile pharmacophore, a privileged scaffold, and a
remarkable sulphur-containing heterocyclic compound with diverse pharmacological …

Aqueous extracts of biomass ash as an alternative class of Green Solvents for organic transformations: A review update

D Sarmah, KK Borah, U Bora - Sustainable Chemistry and Pharmacy, 2021 - Elsevier
The minimization of generation of wastes or their eradication is a crucial aspect of Green
Chemistry. As such, the design of processes that involve any or both the two, is of utmost …

Computational studies by molecular docking of some antiviral drugs with COVID-19 receptors are an approach to medication for COVID-19

MH Abdellatiif, A Ali, A Ali, MA Hussien - Open Chemistry, 2021 - degruyter.com
The COVID-19 outbreak is a matter of concern worldwide due to unavailability of promising
treatment comprising medication or vaccination till date. The discovery of antiviral drug is of …

A synergetic role of Aegle marmelos fruit ash in the synthesis of biscoumarins and 2-amino-4H-chromenes

RC Patil, SK Shinde, UP Patil, AT Birajdar… - Research on Chemical …, 2021 - Springer
A dry rind of Aegle marmelos (bael) fruit ash as a synergetic alternative material to an
expensive, toxic and corrosive catalysts for the synthesis of biscoumarins and 2-amino-4 H …