Antibiotic adjuvants: a versatile approach to combat antibiotic resistance

G Dhanda, Y Acharya, J Haldar - ACS omega, 2023 - ACS Publications
The problem of antibiotic resistance is on the rise, with multidrug-resistant strains emerging
even to the last resort antibiotics. The drug discovery process is often stalled by stringent cut …

Methicillin-resistant Staphylococcus aureus: molecular characterization, evolution, and epidemiology

S Lakhundi, K Zhang - Clinical microbiology reviews, 2018 - journals.asm.org
Staphylococcus aureus, a major human pathogen, has a collection of virulence factors and
the ability to acquire resistance to most antibiotics. This ability is further augmented by …

The Continuing Threat of Methicillin-Resistant Staphylococcus aureus

M Gajdács - Antibiotics, 2019 - mdpi.com
Staphylococcus aureus has been an exceptionally successful pathogen, which is still
relevant in modern age-medicine due to its adaptability and tenacity. This bacterium may be …

Molecular mechanisms of antibiotic resistance

JMA Blair, MA Webber, AJ Baylay, DO Ogbolu… - Nature reviews …, 2015 - nature.com
Antibiotic-resistant bacteria that are difficult or impossible to treat are becoming increasingly
common and are causing a global health crisis. Antibiotic resistance is encoded by several …

A review of the influence of treatment strategies on antibiotic resistant bacteria and antibiotic resistance genes

VK Sharma, N Johnson, L Cizmas, TJ McDonald… - Chemosphere, 2016 - Elsevier
Antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARG) in the aquatic
environment have become an emerging contaminant issue, which has implications for …

Coagulase-negative staphylococci

K Becker, C Heilmann, G Peters - Clinical microbiology reviews, 2014 - journals.asm.org
The definition of the heterogeneous group of coagulase-negative staphylococci (CoNS) is
still based on diagnostic procedures that fulfill the clinical need to differentiate between …

Staphylococcal chromosomal cassettes mec (SCCmec): A mobile genetic element in methicillin-resistant Staphylococcus aureus

J Liu, D Chen, BM Peters, L Li, B Li, Z Xu… - Microbial …, 2016 - Elsevier
Highlights•MRSA has been one of the major recent infectious pathogens and thus poses a
challenge to hospital infection control.•SCCmec plays a core role in the antimicrobial …

Bacteria from animals as a pool of antimicrobial resistance genes

MA Argudín, A Deplano, A Meghraoui, M Dodémont… - Antibiotics, 2017 - mdpi.com
Antimicrobial agents are used in both veterinary and human medicine. The intensive use of
antimicrobials in animals may promote the fixation of antimicrobial resistance genes in …

Bacterial antimicrobial metal ion resistance

JL Hobman, LC Crossman - Journal of medical …, 2015 - microbiologyresearch.org
Metals such as mercury, arsenic, copper and silver have been used in various forms as
antimicrobials for thousands of years with until recently, little understanding of their mode of …

The emergence of mecC methicillin-resistant Staphylococcus aureus

GK Paterson, EM Harrison, MA Holmes - Trends in microbiology, 2014 - cell.com
The report of methicillin-resistant Staphylococcus aureus (MRSA) encoding a divergent
mecA gene in 2011 was highly significant. This homologue, designated mecC, poses …