Advances in designing and develo** vaccines, drugs, and therapies to counter Ebola virus

K Dhama, K Karthik, R Khandia, S Chakraborty… - Frontiers in …, 2018 - frontiersin.org
Ebola virus (EBOV), a member of the family Filoviridae, is responsible for causing Ebola
virus disease (EVD)(formerly named Ebola hemorrhagic fever). This is a severe, often fatal …

Ebola virus–epidemiology, diagnosis, and control: threat to humans, lessons learnt, and preparedness plans–an update on its 40 year's journey

RK Singh, K Dhama, YS Malik… - Veterinary …, 2017 - Taylor & Francis
Ebola virus (EBOV) is an extremely contagious pathogen and causes lethal hemorrhagic
fever disease in man and animals. The recently occurred Ebola virus disease (EVD) …

New 1, 3, 4-thiadiazole derivatives as α-glucosidase inhibitors: design, synthesis, DFT, ADME, and in vitro enzymatic studies

Z Ali, W Rehman, L Rasheed, AY Alzahrani, N Ali… - ACS …, 2024 - ACS Publications
Diabetes is an emerging disorder in the world and is caused due to the imbalance of insulin
production as well as serious effects on the body. In search of a better treatment for diabetes …

In silico Study of Antiviral Activity of Polyphenol Compounds from Ocimum basilicum by Molecular Docking, ADMET, and Drug-Likeness Analysis

D Kurnia, SA Putri, SG Tumilaar… - … and Applications in …, 2023 - Taylor & Francis
Aim The SARS-CoV-2 virus is a disease that has mild to severe effects on patients, which
can even lead to death. One of the enzymes that act as DNA replication is the main …

[PDF][PDF] Studi in silico potensi senyawa katekin teh hijau (Camellia sinensis) sebagai antivirus SARS CoV-2 terhadap spike glycoprotein (6LZG) dan main protease …

F Naufa, R Mutiah, Y Yen, A Indrawijaya - J. Food Pharm. Sci, 2022 - scholar.archive.org
COVID-19 merupakan penyakit yang disebabkan oleh SARS CoV-2 dengan memproduksi
protein struktural dan protein non-struktural. SARS CoV-2 menggunakan spike glycoprotein …

Phenolic Compounds from Ocimum basilicum Revealed as Antibacterial by Experimental and Computational Screening‐Based Studies against Oral Infections

SA Putri, E Julaeha, N Kagawa… - Journal of Chemistry, 2024 - Wiley Online Library
Dental infections are initiated by Streptococcus sanguinis and Streptococcus mutans
through the biofilm formation. In streptococcal, the ComA enzyme catalyzes the first step to …

Molecular modelling studies on adamantane-based Ebola virus GP-1 inhibitors using docking, pharmacophore and 3D-QSAR

SN Mali, HK Chaudhari - SAR and QSAR in Environmental …, 2019 - Taylor & Francis
The pathogenic Ebola virus (EBOV) causes a potential health risk and global spread. To
date, few drugs are available for the treatment of Ebola virus disease (EVD) that allow …

Therapeutic strategies against ebola virus infection

CH Liu, YT Hu, SH Wong, LT Lin - Viruses, 2022 - mdpi.com
Since the 2014–2016 epidemic, Ebola virus (EBOV) has spread to several countries and
has become a major threat to global health. EBOV is a risk group 4 pathogen, which …

Molecular docking enabled updated screening of the matrix protein VP40 from Ebola virus with millions of compounds in the MCULE database for potential inhibitors

HA Odhar, AM Rayshan, SW Ahjel, AA Hashim… - …, 2019 - pmc.ncbi.nlm.nih.gov
Ebola virus is known for several outbreaks of hemorrhagic fever in West Africa. This RNA
virus is linked to high fatality and easy transmission. Recently, an effective vaccine and a …

EBOLApred: A machine learning-based web application for predicting cell entry inhibitors of the Ebola virus

J Adams, K Agyenkwa-Mawuli, O Agyapong… - … Biology and Chemistry, 2022 - Elsevier
Ebola virus disease (EVD) is a highly virulent and often lethal illness that affects humans
through contact with the body fluid of infected persons. Glycoprotein and matrix protein VP40 …