Incomplete response to Anti-VEGF therapy in neovascular AMD: Exploring disease mechanisms and therapeutic opportunities

PS Mettu, MJ Allingham, SW Cousins - Progress in retinal and eye …, 2021 - Elsevier
Intravitreal anti-vascular endothelial growth factor (VEGF) drugs have revolutionized the
treatment of neovascular age-related macular degeneration (NVAMD). However, many …

Animal models of age related macular degeneration

ME Pennesi, M Neuringer, RJ Courtney - Molecular aspects of medicine, 2012 - Elsevier
Age related macular degeneration (AMD) is the leading cause of vision loss of those over
the age of 65 in the industrialized world. The prevalence and need to develop effective …

Age-related macular degeneration: etiology, pathogenesis, and therapeutic strategies

J Ambati, BK Ambati, SH Yoo, S Ianchulev… - Survey of …, 2003 - Elsevier
Age-related macular degeneration is the principal cause of registered legal blindness
among those aged over 65 in the United States, western Europe, Australia, and Japan …

Choroidal neovascularization

HE Grossniklaus, WR Green - American journal of ophthalmology, 2004 - Elsevier
PURPOSE: To fax: 404-778-5089; review clinicopathologic findings of choroidal
neovascularization (CNV) in a historical framework with emphasis on pathobiology and …

Angiogenesis and chronic inflammation: cause or consequence?

C Costa, J Incio, R Soares - Angiogenesis, 2007 - Springer
Evidence has been gathered regarding the association between angiogenesis and
inflammation in pathological situations. These two phenomena have long been coupled …

Macrophage depletion diminishes lesion size and severity in experimental choroidal neovascularization

DG Espinosa-Heidmann, IJ Suner… - … & visual science, 2003 - iovs.arvojournals.org
purpose. Macrophage recruitment to the choroid has been proposed to contribute to the
pathogenesis of choroidal neovascularization (CNV) in AMD. The study was conducted to …

Choroidal neovascularization in pathological myopia

K Neelam, CMG Cheung, K Ohno-Matsui… - Progress in retinal and …, 2012 - Elsevier
Myopic choroidal neovascularization (CNV) is one of the leading causes of visual
impairment worldwide. The clinical and socioeconomic impact of myopic CNV in Asian …

Intraocular pressure after intravitreal injection of triamcinolone acetonide

JB Jonas, I Kreissig, R Degenring - British journal of ophthalmology, 2003 - bjo.bmj.com
Aim: To investigate the intraocular pressure (IOP) response after intravitreal injections of
triamcinolone acetonide as treatment of intraocular neovascular or oedematous diseases …

Intravitreal injection of therapeutic agents

GA Peyman, EM Lad, DM Moshfeghi - Retina, 2009 - journals.lww.com
Background: Intravitreal injection (IVI) with administration of various pharmacological agents
is a mainstay of treatment in ophthalmology for endopthalmitis, viral retinitis, age-related …

Targeting angiogenesis, the underlying disorder in neovascular age-related macular degeneration

EWM Ng, AP Adamis - Canadian Journal of Ophthalmology, 2005 - Elsevier
Angiogenesis has a causal role in many diseases, including neovascular age-related
macular degeneration (AMD). Identification of key regulators of angiogenesis, including …