Breast milk oligosaccharides: structure-function relationships in the neonate

JT Smilowitz, CB Lebrilla, DA Mills… - Annual review of …, 2014 - annualreviews.org
In addition to providing complete postnatal nutrition, breast milk is a complex biofluid that
delivers bioactive components for the growth and development of the intestinal and immune …

Oligosaccharide analysis by mass spectrometry: a review of recent developments

MJ Kailemia, LR Ruhaak, CB Lebrilla… - Analytical …, 2014 - ACS Publications
Carbohydrates are central players in a number of important biological processes including
cell signaling, cell adhesion, and the regulation of biochemical pathways. Unlike nucleic …

Human milk glycobiome and its impact on the infant gastrointestinal microbiota

AM Zivkovic, JB German, CB Lebrilla… - Proceedings of the …, 2011 - pnas.org
Human milk contains an unexpected abundance and diversity of complex oligosaccharides
apparently indigestible by the develo** infant and instead targeted to its cognate …

Article Commentary: The influence of early infant-feeding practices on the intestinal microbiome and body composition in infants

A O'Sullivan, M Farver… - Nutrition and metabolic …, 2015 - journals.sagepub.com
Despite many years of widespread international recommendations to support exclusive
breastfeeding for the first six months of life, common hospital feeding and birthing practices …

Bifidobacteria isolated from infants and cultured on human milk oligosaccharides affect intestinal epithelial function

M Chichlowski, G De Lartigue, JB German… - Journal of pediatric …, 2012 - journals.lww.com
Objectives: Human milk oligosaccharides (HMOs) are the third most abundant component of
breast milk. Our laboratory has previously revealed gene clusters specifically linked to HMO …

Milk intelligence: Mining milk for bioactive substances associated with human health

S Mills, RP Ross, C Hill, GF Fitzgerald… - International dairy journal, 2011 - Elsevier
Milk has evolved as a complete food for the mammalian nourishment of its young. However,
research is unveiling an ever-accumulating range of bioactivities associated with milk …

Human milk glycomics and gut microbial genomics in infant feces show a correlation between human milk oligosaccharides and gut microbiota: a proof-of-concept …

MLA De Leoz, KM Kalanetra, NA Bokulich… - Journal of proteome …, 2015 - ACS Publications
Human milk oligosaccharides (HMOs) play a key role in sha** and maintaining a healthy
infant gut microbiota. This article demonstrates the potential of combining recent advances …

Bifidobacterium longum subsp. infantis ATCC 15697 α-fucosidases are active on fucosylated human milk oligosaccharides

DA Sela, D Garrido, L Lerno, S Wu, K Tan… - Applied and …, 2012 - journals.asm.org
Bifidobacterium longum subsp. infantis ATCC 15697 utilizes several small-mass neutral
human milk oligosaccharides (HMOs), several of which are fucosylated. Whereas previous …

Human milk oligosaccharides: evolution, structures and bioselectivity as substrates for intestinal bacteria

JB German, SL Freeman, CB Lebrilla… - Nestle Nutrition …, 2008 - pmc.ncbi.nlm.nih.gov
Human milk contains a high concentration of diverse soluble oligosaccharides that are
carbohydrate polymers formed from a relatively small number of different monosaccharides …