Antimicrobial peptides–Advances in development of therapeutic applications

HX Luong, TT Thanh, TH Tran - Life sciences, 2020 - Elsevier
The severe infection is becoming a significant health problem which threaten the lives of
patients and the safety and economy of society. In the way of finding new strategy …

Design and use of model membranes to study biomolecular interactions using complementary surface-sensitive techniques

LA Clifton, RA Campbell, F Sebastiani… - Advances in Colloid and …, 2020 - Elsevier
Cellular membranes are complex structures and simplified analogues in the form of model
membranes or biomembranes are used as platforms to understand fundamental properties …

[HTML][HTML] Natural peptides inducing cancer cell death: Mechanisms and properties of specific candidates for cancer therapeutics

PA Trinidad-Calderón, CD Varela-Chinchilla… - Molecules, 2021 - mdpi.com
Nowadays, cancer has become the second highest leading cause of death, and it is
expected to continue to affect the population in forthcoming years. Additionally, treatment …

Renovation as innovation: Repurposing human antibacterial peptide LL-37 for cancer therapy

F Lu, Y Zhu, G Zhang, Z Liu - Frontiers in Pharmacology, 2022 - frontiersin.org
In many organisms, antimicrobial peptides (AMPs) display wide activities in innate host
defense against microbial pathogens. Mammalian AMPs include the cathelicidin and …

Effect of substituting glutamine with lysine on structural and biological properties of antimicrobial peptide Polybia-MP1

HBT Phuong, VA Tran, KN Ngoc, VN Huu, HN Thu… - Amino Acids, 2023 - Springer
The natural antimicrobial peptide Polybia-MP1 is a promising candidate for develo** new
treatment therapy for infection and cancer. It showed broad-spectrum antimicrobial and …

The phase and charge of milk polar lipid membrane bilayers govern their selective interactions with proteins as demonstrated with casein micelles

S Obeid, F Guyomarc'h, E David-Briand… - Journal of colloid and …, 2019 - Elsevier
The biological membrane surrounding fat globules in milk (milk fat globule membrane;
MFGM) is an interface involved in many biological functions and interactions with the …

Chemical approaches in the development of natural nontoxic peptide Polybia-MP1 as a potential dual antimicrobial and antitumor agent

HL Xuan, TD Duc, AM Thuy, PM Chau, TT Tung - Amino Acids, 2021 - Springer
Polybia-MP1 is a well-known natural antimicrobial peptide that has been intensively studied
recently due to its therapeutic potential. MP1 exhibited not only potent antibacterial activity …

[HTML][HTML] Biophysical characterization of the insertion of two potent antimicrobial peptides-Pin2 and its variant Pin2 [GVG] in biological model membranes

B Bertrand, S Munusamy, JF Espinosa-Romero… - … et Biophysica Acta (BBA …, 2020 - Elsevier
The aim of this study was to investigate the factors that govern the activity and selectivity of
two potent antimicrobial peptides (AMPs) using lipid membrane models of bacterial …

Whey-Derived Antimicrobial Anionic Peptide Interaction with Model Membranes and Cells

MM Noe, JA Rodríguez, GR Barredo Vacchelli… - Langmuir, 2025 - ACS Publications
The present work focuses on one of the possible target mechanisms of action of the anionic
antimicrobial peptide β-lg125–135 derived from trypsin hydrolysis of β-lactoglobulin. After …

[HTML][HTML] Interaction of Artepillin C with model membranes: effects of pH and ionic strength

WM Pazin, GCM Ruiz, ON de Oliveira Jr… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Artepillin C is the major constituent of green propolis, one of the most consumed products in
popular medicine owing to its therapeutic effects, including antitumor activity. Artepillin C …