Eosinophils play a homeostatic role in the body's immune responses. These cells are
involved in combating some parasitic, bacterial, and viral infections and certain cancers and …

Allergic asthma is among the most common immune-mediated diseases across the world,
and type 2 immune responses are thought to be central to pathogenesis. The importance of …

Asthma is a prevalent chronic non-communicable disease, affecting approximately 300
million people worldwide. It is characterized by significant airway inflammation …

Chronic rhinosinusitis with nasal polyps (CRSwNP) is generally associated with eosinophilic
tissue infiltration linked to type 2 inflammation and characterized by elevated levels of …

The human eosinophil has long been thought to favorably influence innate mucosal
immunity but at times has also been incriminated in disease pathophysiology. Research into …

INTRODUCTION Spontaneous protein crystallization rarely occurs in vivo. When it does,
crystals are generated, which sustain long-term protein storage or enable the slow release …

abstract IL-5 is the most potent activator of eosinophils and is produced by Th2 cells and
ILC2s. A role for IL-5 in eosinophil extracellular trap cell death, ie, a proinflammatory cell …

Chronic rhinosinusitis (CRS) occurs in> 10% of the adult population in Europe and the USA
and can be differentiated into CRS without nasal polyps and CRS with nasal polyps …

Eosinophilic inflammation is a feature of allergic asthma. Despite mounting evidence
showing that chromatin filaments released from neutrophils mediate various diseases, the …

Chronic rhinosinusitis (CRS) often is characterized by an eosinophilic inflammatory pattern,
nowadays referred to as type 2 inflammation, although the mucosal inflammation is …