Nanocarriers address intracellular barriers for efficient drug delivery, overcoming drug resistance, subcellular targeting and controlled release

J Liu, H Cabral, P Mi - Advanced Drug Delivery Reviews, 2024 - Elsevier
The cellular barriers are major bottlenecks for bioactive compounds entering into cells to
accomplish their biological functions, which limits their biomedical applications …

Mechanisms and barriers in nanomedicine: progress in the field and future directions

T Anchordoquy, N Artzi, IV Balyasnikova, Y Barenholz… - ACS …, 2024 - ACS Publications
In recent years, steady progress has been made in synthesizing and characterizing
engineered nanoparticles, resulting in several approved drugs and multiple promising …

Liver cirrhosis: molecular mechanisms and therapeutic interventions

Z Dong, Y Wang, W ** - MedComm, 2024 - Wiley Online Library
Liver cirrhosis is the end‐stage of chronic liver disease, characterized by inflammation,
necrosis, advanced fibrosis, and regenerative nodule formation. Long‐term inflammation …

Intracellular delivery of piezotronic-dominated nanocatalysis to mimic mitochondrial ROS generation for powering macrophage immunotherapy

J Feng, X Liu, K Li, W Zhao, W Wang, S Ge, H Liu, J Li - Nano Energy, 2024 - Elsevier
Macrophages are the first line of host defense against bacterial infections and mitochondrial
reactive oxygen species (mROS) plays an important role in the bactericidal innate response …

Learning what keeps nanomedicines in tumours

Y Wang, BR Schrank, W Jiang, BYS Kim - Nature Biomedical …, 2024 - nature.com
An analysis of histopathological data from mouse and human tumours via machine learning
reveals that the densities of blood vessels and tumour-associated macrophages are …

[HTML][HTML] Targeted nanomedicine for reprogramming the tumor innate immune system: From bench to bedside

K Pednekar, J Minnee, IJM de Vries… - European Journal of …, 2024 - Elsevier
Tumor-associated innate immune cells such as tumor-associated macrophages, neutrophils,
dendritic cells play a crucial role in tumor progression, angiogenesis and metastasis. These …

[HTML][HTML] Advances in medical devices using nanomaterials and nanotechnology: Innovation and regulatory science

C Lin, X Huang, Y Xue, S Jiang, C Chen, Y Liu… - Bioactive Materials, 2025 - Elsevier
Nanomaterials and nanotechnology are emerging as promising strategies for medical
devices due to their advantageous properties, including the ability to effectively interact with …