Embracing diversity in the 5-HT neuronal system
BW Okaty, KG Commons, SM Dymecki - Nature Reviews Neuroscience, 2019 - nature.com
Neurons that synthesize and release 5-hydroxytryptamine (5-HT; serotonin) express a core
set of genes that establish and maintain this neurotransmitter phenotype and distinguish …
set of genes that establish and maintain this neurotransmitter phenotype and distinguish …
[HTML][HTML] Serotonin in the modulation of neural plasticity and networks: implications for neurodevelopmental disorders
KP Lesch, J Waider - Neuron, 2012 - cell.com
Serotonin (5-HT) shapes brain networks during development and modulates a wide
spectrum of essential neuronal functions ranging from perception and cognitive appraisal to …
spectrum of essential neuronal functions ranging from perception and cognitive appraisal to …
Distinct serotonergic pathways to the amygdala underlie separate behavioral features of anxiety
Anxiety-like behaviors in mice include social avoidance and avoidance of bright spaces.
Whether these features are distinctly regulated is unclear. We demonstrate that in mice …
Whether these features are distinctly regulated is unclear. We demonstrate that in mice …
Single-cell transcriptomes and whole-brain projections of serotonin neurons in the mouse dorsal and median raphe nuclei
Serotonin neurons of the dorsal and median raphe nuclei (DR, MR) collectively innervate
the entire forebrain and midbrain, modulating diverse physiology and behavior. To gain a …
the entire forebrain and midbrain, modulating diverse physiology and behavior. To gain a …
Single-cell activity and network properties of dorsal raphe nucleus serotonin neurons during emotionally salient behaviors
The serotonin system modulates a wide variety of emotional behaviors and states, including
reward processing, anxiety, and social interaction. To reveal the underlying patterns of …
reward processing, anxiety, and social interaction. To reveal the underlying patterns of …
Anatomically defined and functionally distinct dorsal raphe serotonin sub-systems
The dorsal raphe (DR) constitutes a major serotonergic input to the forebrain and modulates
diverse functions and brain states, including mood, anxiety, and sensory and motor …
diverse functions and brain states, including mood, anxiety, and sensory and motor …
Serotonin neurons in the dorsal raphe nucleus encode reward signals
The dorsal raphe nucleus (DRN) is involved in organizing reward-related behaviours;
however, it remains unclear how genetically defined neurons in the DRN of a freely …
however, it remains unclear how genetically defined neurons in the DRN of a freely …
Molecular and anatomical organization of the dorsal raphe nucleus
The dorsal raphe nucleus (DRN) is an important source of neuromodulators and has been
implicated in a wide variety of behavioral and neurological disorders. The DRN is …
implicated in a wide variety of behavioral and neurological disorders. The DRN is …
Presynaptic partners of dorsal raphe serotonergic and GABAergic neurons
B Weissbourd, J Ren, KE DeLoach, CJ Guenthner… - Neuron, 2014 - cell.com
The serotonin system powerfully modulates physiology and behavior in health and disease,
yet the circuit mechanisms underlying serotonin neuron activity are poorly understood. The …
yet the circuit mechanisms underlying serotonin neuron activity are poorly understood. The …
Conditional anterograde tracing reveals distinct targeting of individual serotonin cell groups (B5–B9) to the forebrain and brainstem
A Muzerelle, S Scotto-Lomassese, JF Bernard… - Brain Structure and …, 2016 - Springer
Serotoninergic innervation of the central nervous system is provided by hindbrain raphe
nuclei (B1–B9). The extent to which each raphe subdivision has distinct topographic …
nuclei (B1–B9). The extent to which each raphe subdivision has distinct topographic …