Principles of TAVR valve design, modelling, and testing

OM Rotman, M Bianchi, RP Ghosh… - Expert review of …, 2018 - Taylor & Francis
Introduction: Transcatheter aortic valve replacement (TAVR) has emerged as an effective
minimally-invasive alternative to surgical valve replacement in medium-to high-risk, elderly …

Bioprosthetic Aortic Valve Hemodynamics: Definitions, Outcomes, and Evidence Gaps: JACC State-of-the-Art Review

HC Herrmann, P Pibarot, C Wu, RT Hahn… - Journal of the American …, 2022 - jacc.org
A virtual workshop was organized by the Heart Valve Collaboratory to identify areas of
expert consensus, areas of disagreement, and evidence gaps related to bioprosthetic aortic …

Deformation of transcatheter aortic valve prostheses: implications for hypoattenuating leaflet thickening and clinical outcomes

M Fukui, VN Bapat, S Garcia, MW Dworak… - Circulation, 2022 - Am Heart Assoc
Background: Although transcatheter aortic valve replacement (TAVR) therapy continues to
grow, there have been concerns about the occurrence of hypoattenuating leaflet thickening …

Patient-specific simulation of transcatheter aortic valve replacement: impact of deployment options on paravalvular leakage

M Bianchi, G Marom, RP Ghosh, OM Rotman… - … and modeling in …, 2019 - Springer
Transcatheter aortic valve replacement (TAVR) has emerged as an effective alternative to
conventional surgical valve replacement in high-risk patients afflicted by severe aortic …

Thinner biological tissues induce leaflet flutter in aortic heart valve replacements

EL Johnson, MCH Wu, F Xu… - Proceedings of the …, 2020 - National Acad Sciences
Valvular heart disease has recently become an increasing public health concern due to the
high prevalence of valve degeneration in aging populations. For patients with severely …

5-year outcomes with self-expanding vs balloon-expandable transcatheter aortic valve replacement in patients with small annuli

T Okuno, D Tomii, J Lanz, D Heg, F Praz… - Cardiovascular …, 2023 - jacc.org
Background Self-expanding transcatheter heart valves (THVs) are associated with better
echocardiographic hemodynamic performance than balloon-expandable THVs and are …

Novel Polymeric Valve for Transcatheter Aortic Valve Replacement Applications: In Vitro Hemodynamic Study

OM Rotman, B Kovarovic, WC Chiu, M Bianchi… - Annals of biomedical …, 2019 - Springer
Transcatheter aortic valve replacement (TAVR) is a minimally-invasive approach for treating
severe aortic stenosis. All clinically-used TAVR valves to date utilize chemically-fixed …

[HTML][HTML] Impact of patient-specific morphologies on sinus flow stasis in transcatheter aortic valve replacement: an in vitro study

H Hatoum, J Dollery, SM Lilly, J Crestanello… - The Journal of thoracic …, 2019 - Elsevier
Objective The goal of this study is to evaluate how sinus flow patterns after transcatheter
aortic valve replacement in realistic representative patient roots vary. Sinus flow can affect …

[HTML][HTML] Bioinspired NiTi-reinforced polymeric heart valve exhibiting excellent hemodynamics and reduced stress

S Chen, B Zhang, J Hu, X Zheng, S Qin, C Li… - Composites Part B …, 2023 - Elsevier
The durability of the current polymeric heart valves remains to be improved, which has
proven to be highly dynamics and species dependent. Herein, inspired by the fiber …

Transcatheter aortic valve replacement for structural degeneration of previously implanted transcatheter valves (TAVR-in-TAVR): a systematic review

M Gallo, LN Fovino, D Blitzer… - European Journal of …, 2022 - academic.oup.com
OBJECTIVES Transcatheter aortic valve replacement (TAVR) represents a valid treatment
for patients with aortic valve stenosis and high or intermediate surgical risk. However …