Antithrombotic strategies targeting thrombin activities, thrombin receptors and thrombin generation

LA Harker, SR Hanson, AB Kelly - Thrombosis and haemostasis, 1997 - thieme-connect.com
Division of Hemalology and Oncology; and Yerkes Regional Primate Research Center,
Emory University School of Medicine, Atlanta, GA, USA lntroduction Platelet recruitment in …

Anticoagulants: Inhibitors of the factor vila/tissue factor pathway

LA Robinson, EMK Saiah - 2002 - Elsevier
Introduction-The coagulation cascade has been the subject of intensive investigation over
the last two decades and has been extensively reviewed (1). While tremendous progress …

Therapeutic inhibition of thrombin activities, receptors, and production

LA Harker - Hematology/oncology clinics of North America, 1998 - Elsevier
Mechanical disruption of blood vessels initiates localized hemostatic and thrombotic
responses involving endothelial, platelet, coagulation, and fibrinolytic pathways (Fig. 1). 8 …