Brain imaging in comatose survivors of cardiac arrest: pathophysiological correlates and prognostic properties

HM Keijzer, CWE Hoedemaekers, FJA Meijer… - Resuscitation, 2018‏ - Elsevier
Introduction Hypoxic-ischemic brain injury is the main cause of death and disability of
comatose patients after cardiac arrest. Early and reliable prognostication is challenging …

Treating rhythmic and periodic EEG patterns in comatose survivors of cardiac arrest

BJ Ruijter, HM Keijzer… - … England Journal of …, 2022‏ - Mass Medical Soc
Background Whether the treatment of rhythmic and periodic electroencephalographic (EEG)
patterns in comatose survivors of cardiac arrest improves outcomes is uncertain. Methods …

EEG in postanoxic coma: prognostic and diagnostic value

J Hofmeijer, MJAM van Putten - Clinical neurophysiology, 2016‏ - Elsevier
Evolution of the EEG background pattern is a robust contributor to prediction of poor or good
outcome of comatose patients after cardiac arrest. At 24 h, persistent isoelectricity, low …

Hypoxic-ischemic encephalopathy evaluated by brain autopsy and neuroprognostication after cardiac arrest

C Endisch, E Westhall, M Kenda, KJ Streitberger… - JAMA …, 2020‏ - jamanetwork.com
Importance Neuroprognostication studies are potentially susceptible to a self-fulfilling
prophecy as investigated prognostic parameters may affect withdrawal of life-sustaining …

Generalized epileptiform discharges in postanoxic encephalopathy: quantitative characterization in relation to outcome

BJ Ruijter, MJAM Van Putten, J Hofmeijer - Epilepsia, 2015‏ - Wiley Online Library
Objective Electrographic status epilepticus is observed in 10–35% of patients with
postanoxic encephalopathy. It remains unclear which electrographic seizure patterns …

Modulation of synaptic plasticity by exercise training as a basis for ischemic stroke rehabilitation

J Nie, X Yang - Cellular and molecular neurobiology, 2017‏ - Springer
In recent years, rehabilitation of ischemic stroke draws more and more attention in the world,
and has been linked to changes of synaptic plasticity. Exercise training improves motor …

Time to epileptiform activity and EEG background recovery are independent predictors after cardiac arrest

E Westhall, I Rosén, M Rundgren, J Bro-Jeppesen… - Clinical …, 2018‏ - Elsevier
Objective Investigate the temporal development of EEG and prognosis. Methods Prospective
observational substudy of the Target Temperature Management trial. Six sites performed …

EEG monitoring in cerebral ischemia: basic concepts and clinical applications

MJAM van Putten, J Hofmeijer - Journal of clinical …, 2016‏ - journals.lww.com
EEG is very sensitive to changes in neuronal function resulting from ischemia. The authors
briefly review essentials of EEG generation and the effects of ischemia on the underlying …

[HTML][HTML] Generalized periodic discharges: pathophysiology and clinical considerations

MJAM van Putten, J Hofmeijer - Epilepsy & behavior, 2015‏ - Elsevier
Generalized periodic discharges (GPDs) are commonly encountered in metabolic
encephalopathy and cerebral hypoxia/ischemia. The clinical significance of this EEG pattern …

Treatment of electroencephalographic status epilepticus after cardiopulmonary resuscitation (TELSTAR): study protocol for a randomized controlled trial

BJ Ruijter, MJAM van Putten, J Horn, MJ Blans… - Trials, 2014‏ - Springer
Background Electroencephalographic (EEG) status epilepticus is described in 10 to 35% of
patients with postanoxic encephalopathy after successful cardiopulmonary resuscitation and …