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Visually sensitive seizures: An updated review by the Epilepsy Foundation
Light flashes, patterns, or color changes can provoke seizures in up to 1 in 4000 persons.
Prevalence may be higher because of selection bias. The Epilepsy Foundation reviewed …
Prevalence may be higher because of selection bias. The Epilepsy Foundation reviewed …
Progress report on new antiepileptic drugs: a summary of the Eigth Eilat Conference (EILAT VIII)
M Bialer, SI Johannessen, HJ Kupferberg, RH Levy… - Epilepsy research, 2007 - Elsevier
The Eigth Eilat Conference on New Antiepileptic Drugs (AEDs)-EILAT VII, took place in
Sitges, Barcelona from the 10th to 14th September, 2006. Basic scientists, clinical …
Sitges, Barcelona from the 10th to 14th September, 2006. Basic scientists, clinical …
Binding characteristics of brivaracetam, a selective, high affinity SV2A ligand in rat, mouse and human brain: relationship to anti-convulsant properties
M Gillard, B Fuks, K Leclercq, A Matagne - European journal of …, 2011 - Elsevier
Brivaracetam is a novel synaptic vesicle protein 2A (SV2A) ligand reported to be 10 fold
more potent than levetiracetam in animal models of epilepsy. This study reports the binding …
more potent than levetiracetam in animal models of epilepsy. This study reports the binding …
Levetiracetam and brivaracetam: a review of evidence from clinical trials and clinical experience
BJ Steinhoff, AM Staack - Therapeutic advances in …, 2019 - journals.sagepub.com
Until the early 1990s, a limited number of antiepileptic drugs (AEDs) were available. Since
then, a large variety of new AEDs have been developed and introduced, several of them …
then, a large variety of new AEDs have been developed and introduced, several of them …
Non-invasive EEG evaluation in epilepsy diagnosis
The EEG is an invaluable tool in the diagnosis of epilepsy which guides clinical
management. It helps to determine if attacks are of epileptic origin, allows the estimation of …
management. It helps to determine if attacks are of epileptic origin, allows the estimation of …
[HTML][HTML] Efficacy, tolerability and safety of add-on third-generation antiseizure medications in treating focal seizures worldwide: A network meta-analysis of randomised …
Y Chen, W Li, C Lu, X Gao, H Song, Y Zhang… - …, 2024 - thelancet.com
Background Adjunctive newer antiseizure medications (ASMs) are being used in patients
with treatment-resistant focal-onset seizures (FOS). An updated network meta-analysis …
with treatment-resistant focal-onset seizures (FOS). An updated network meta-analysis …
Efficacy and tolerability of adjunctive brivaracetam in adults with uncontrolled partial‐onset seizures: a phase IIb, randomized, controlled trial
Purpose: To evaluate the efficacy and tolerability of adjunctive brivaracetam (BRV), a novel
high‐affinity synaptic vesicle protein 2A ligand that also displays inhibitory activity at …
high‐affinity synaptic vesicle protein 2A ligand that also displays inhibitory activity at …
Adjunctive brivaracetam for refractory partial-onset seizures: a randomized, controlled trial
JA French, C Costantini, A Brodsky, P von Rosenstiel - Neurology, 2010 - neurology.org
Objective: To explore efficacy and safety/tolerability of adjunctive brivaracetam (BRV), a
novel, high-affinity synaptic vesicle protein 2A ligand, which also inhibits neuronal voltage …
novel, high-affinity synaptic vesicle protein 2A ligand, which also inhibits neuronal voltage …
Current state of the epilepsy drug and device pipeline
The field of epilepsy has undergone substantial advances as we develop novel drugs and
devices. Yet considerable challenges remain in develo** broadly effective, well‐tolerated …
devices. Yet considerable challenges remain in develo** broadly effective, well‐tolerated …
A review of the pharmacology and clinical efficacy of brivaracetam
Brivaracetam (BRV; Briviact) is a new antiepileptic drug (AED) approved for adjunctive
treatment of focal (partial-onset) seizures in adults. BRV is a selective, high-affinity ligand for …
treatment of focal (partial-onset) seizures in adults. BRV is a selective, high-affinity ligand for …