From the perspective of a chemist, biology confers a rich variety of roles on a number of
metal ions. It is widely agreed that a large fraction of the genomic output of living things …

Selenium is generally known as an antioxidant due to its presence in selenoproteins as
selenocysteine, but it is also toxic. The toxic effects of selenium are, however, strictly …

Multiple biological functions of selenium manifest themselves mainly via 25 selenoproteins
that have selenocysteine at their active centre. Selenium is vital for the brain and seems to …

α-Synuclein plays a central causative role in Parkinson's disease (PD). Increased
expression of the P-type ATPase ion pump PARK9/ATP13A2 suppresses α-Synuclein …

Selenium (Se) is an essential element for maintaining human health. The biological effects
and toxicity of Se compounds in humans are related to their chemical forms and …

Selenium (Se) is known to contribute to several vital physiological functions in mammals:
antioxidant defense, fertility, thyroid hormone metabolism, and immune response. Growing …

Trace metals play important roles in biological function, and x‐ray fluorescence microscopy
(XFM) provides a way to quantitatively image their distribution within cells. The faithfulness …

In this Review, we attempt to give an overview of methods developed for chemical analysis
of single cells. This is an important topic for several reasons. Many biological systems have …

The understanding of the essential role of selenium (Se) in human health has increased
substantially in recent decades. Micronutrient deficiencies are very common in the general …

Small molecule ruthenium complexes show great promise as anticancer pharmaceuticals,
but further rational development of these as drugs is stymied by an incomplete …