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Hyperpolarized 129Xe MRI of the human lung
By permitting direct visualization of the airspaces of the lung, magnetic resonance imaging
(MRI) using hyperpolarized gases provides unique strategies for evaluating pulmonary …
(MRI) using hyperpolarized gases provides unique strategies for evaluating pulmonary …
Imaging of lung function using hyperpolarized helium‐3 magnetic resonance imaging: review of current and emerging translational methods and applications
During the past several years there has been extensive development and application of
hyperpolarized helium‐3 (HP 3He) magnetic resonance imaging (MRI) in clinical respiratory …
hyperpolarized helium‐3 (HP 3He) magnetic resonance imaging (MRI) in clinical respiratory …
Using hyperpolarized 129Xe MRI to quantify regional gas transfer in idiopathic pulmonary fibrosis
Background Assessing functional impairment, therapeutic response and disease
progression in patients with idiopathic pulmonary fibrosis (IPF) continues to be challenging …
progression in patients with idiopathic pulmonary fibrosis (IPF) continues to be challenging …
Regional map** of gas uptake by blood and tissue in the human lung using hyperpolarized xenon‐129 MRI
Purpose To develop a breathhold acquisition for regional map** of ventilation and the
fractions of hyperpolarized xenon‐129 (Xe129) dissolved in tissue (lung parenchyma and …
fractions of hyperpolarized xenon‐129 (Xe129) dissolved in tissue (lung parenchyma and …
Imaging alveolar–capillary gas transfer using hyperpolarized 129Xe MRI
Effective pulmonary gas exchange relies on the free diffusion of gases across the thin tissue
barrier separating airspace from the capillary red blood cells (RBCs). Pulmonary …
barrier separating airspace from the capillary red blood cells (RBCs). Pulmonary …
Quantitative analysis of hyperpolarized 129Xe gas transfer MRI
Purpose Hyperpolarized 129Xe magnetic resonance imaging (MRI) using Dixon‐based
decomposition enables single‐breath imaging of 129Xe in the airspaces, interstitial barrier …
decomposition enables single‐breath imaging of 129Xe in the airspaces, interstitial barrier …
[HTML][HTML] In vivo methods and applications of xenon-129 magnetic resonance
Hyperpolarised gas lung MRI using xenon-129 can provide detailed 3D images of the
ventilated lung airspaces, and can be applied to quantify lung microstructure and detailed …
ventilated lung airspaces, and can be applied to quantify lung microstructure and detailed …
Molecular imaging using hyperpolarized 13C
MRI provides unsurpassed soft tissue contrast, but the inherent low sensitivity of this
modality has limited the clinical use to imaging of water protons. With hyperpolarization …
modality has limited the clinical use to imaging of water protons. With hyperpolarization …
Hyperpolarized 129Xe MR Imaging of Alveolar Gas Uptake in Humans
Background One of the central physiological functions of the lungs is to transfer inhaled
gases from the alveoli to pulmonary capillary blood. However, current measures of alveolar …
gases from the alveoli to pulmonary capillary blood. However, current measures of alveolar …
Pulmonary functional imaging: Part 1—state-of-the-art technical and physiologic underpinnings
Over the past few decades, pulmonary imaging technologies have advanced from chest
radiography and nuclear medicine methods to high-spatial-resolution or low-dose chest CT …
radiography and nuclear medicine methods to high-spatial-resolution or low-dose chest CT …