Priorities for cancer research in low-and middle-income countries: a global perspective
Cancer research currently is heavily skewed toward high-income countries (HICs), with little
research conducted in, and relevant to, the problems of low-and middle-income countries …
research conducted in, and relevant to, the problems of low-and middle-income countries …
Enrollment of racial minorities in clinical trials: old problem assumes new urgency in the age of immunotherapy.
Minority US populations are underrepresented in cancer clinical trials. This review appraises
the impact of the disparity in clinical trial participation by minority patients in the current era …
the impact of the disparity in clinical trial participation by minority patients in the current era …
Interpreting clinical trial data in multiple myeloma: translating findings to the real-world setting
Substantial improvements in survival have been seen in multiple myeloma (MM) over recent
years, associated with the introduction and widespread use of multiple novel agents and …
years, associated with the introduction and widespread use of multiple novel agents and …
Problems with the collection and interpretation of Asian-American health data: omission, aggregation, and extrapolation
AT Holland, LP Palaniappan - Annals of epidemiology, 2012 - Elsevier
Asian-American citizens are the fastest growing racial/ethnic group in the United States.
Nevertheless, data on Asian American health are scarce, and many health disparities for this …
Nevertheless, data on Asian American health are scarce, and many health disparities for this …
The role of drug metabolizing enzymes in clearance
L Di - Expert opinion on drug metabolism & toxicology, 2014 - Taylor & Francis
Introduction: Metabolism is one of the most important clearance pathways representing the
major clearance route of 75% drugs. The four most common drug metabolizing enzymes …
major clearance route of 75% drugs. The four most common drug metabolizing enzymes …
Racial differences in cancer susceptibility and survival: more than the color of the skin?
BC Özdemir, GP Dotto - Trends in cancer, 2017 - cell.com
Epidemiological studies point to race as a determining factor in cancer susceptibility. In US
registries recording cancer incidence and survival by race (distinguishing 'black versus …
registries recording cancer incidence and survival by race (distinguishing 'black versus …
Dialogues on diversifying clinical trials: successful strategies for engaging women and minorities in clinical trials
M Coakley, EO Fadiran, LJ Parrish… - Journal of women's …, 2012 - liebertpub.com
There is mounting scientific evidence pointing to genetic or physiologic distinctions between
genders and among racial and ethnic groups that influence disease risk and severity and …
genders and among racial and ethnic groups that influence disease risk and severity and …
Geographic differences in gut microbiota composition impact susceptibility to enteric infection
Large-scale studies of human gut microbiomes have revealed broad differences in
composition across geographically distinct populations. Yet, studies examining impacts of …
composition across geographically distinct populations. Yet, studies examining impacts of …
Herbal interaction with chemotherapeutic drugs—a focus on clinically significant findings
PS Fasinu, GK Rapp - Frontiers in oncology, 2019 - frontiersin.org
One of the most consequential risks associated with the concomitant use of herbal products
and chemotherapeutic agents is herb-drug interactions. The risk is higher in patients with …
and chemotherapeutic agents is herb-drug interactions. The risk is higher in patients with …
Pazopanib in advanced soft tissue sarcomas
Pazopanib is the first and only tyrosine kinase inhibitor currently approved for the treatment
of multiple histological subtypes of soft tissue sarcoma (STS). Initially developed as a small …
of multiple histological subtypes of soft tissue sarcoma (STS). Initially developed as a small …