[HTML][HTML] Programmed necrotic cell death of macrophages: Focus on pyroptosis, necroptosis, and parthanatos

N Robinson, R Ganesan, C Hegedűs, K Kovács… - Redox biology, 2019‏ - Elsevier
Macrophages are highly plastic cells of the innate immune system. Macrophages play
central roles in immunity against microbes and contribute to a wide array of pathologies. The …

Kaempferol and inflammation: From chemistry to medicine

KP Devi, DS Malar, SF Nabavi, A Sureda, J **ao… - Pharmacological …, 2015‏ - Elsevier
Inflammation is an important process of human healing response, wherein the tissues
respond to injuries induced by many agents including pathogens. It is characterized by pain …

Mitochondria-Targeting Multifunctional Fluorescent Probe toward Polarity, Viscosity, and ONOO and Cell Imaging

Y Huang, M Li, Q Zan, R Wang, S Shuang… - Analytical …, 2023‏ - ACS Publications
Abnormal changes occurring in the mitochondrial microenvironment are important markers
indicating mitochondrial and cell dysfunction. Herein, we designed and synthesized a …

Therapeutic targets of oxidative/nitrosative stress and neuroinflammation in ischemic stroke: Applications for natural product efficacy with omics and systemic biology

H Chen, Y He, S Chen, S Qi, J Shen - Pharmacological Research, 2020‏ - Elsevier
Oxidative/nitrosative stress and neuroinflammation are critical pathological processes in
cerebral ischemia-reperfusion injury, and their intimate interactions mediate neuronal …

[HTML][HTML] The interplay of oxidative stress and ROS scavenging: antioxidants as a therapeutic potential in sepsis

S Kumar, J Saxena, VK Srivastava, S Kaushik, H Singh… - Vaccines, 2022‏ - mdpi.com
Oxidative stress resulting from the disproportion of oxidants and antioxidants contributes to
both physiological and pathological conditions in sepsis. To combat this, the antioxidant …

Nitric oxide and peroxynitrite in health and disease

P Pacher, JS Beckman, L Liaudet - Physiological reviews, 2007‏ - journals.physiology.org
The discovery that mammalian cells have the ability to synthesize the free radical nitric oxide
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …

Peroxynitrite: biochemistry, pathophysiology and development of therapeutics

C Szabó, H Ischiropoulos, R Radi - Nature reviews Drug discovery, 2007‏ - nature.com
Peroxynitrite—the product of the diffusion-controlled reaction of nitric oxide with superoxide
radical—is a short-lived oxidant species that is a potent inducer of cell death. Conditions in …

Reactive oxygen species, aging, and antioxidative nutraceuticals

J Lee, N Koo, DB Min - … reviews in food science and food safety, 2004‏ - Wiley Online Library
The important roles of reactive oxygen species in diseases related to aging and the
necessity and benefits of antioxidative nutraceuticals in the prevention of diseases and …

Catechin, epicatechin, quercetin, rutin and resveratrol in red grape: Content, in vitro antioxidant activity and interactions

P Iacopini, M Baldi, P Storchi, L Sebastiani - Journal of Food Composition …, 2008‏ - Elsevier
The extracts obtained from skin and seeds of 10 native Tuscan and international Vitis
vinifera varieties were evaluated for their antioxidant activity, total phenolic and anthocyanin …

X‐Ray‐Controlled Generation of Peroxynitrite Based on Nanosized LiLuF4:Ce3+ Scintillators and their Applications for Radiosensitization

Z Du, X Zhang, Z Guo, J **e, X Dong, S Zhu… - Advanced …, 2018‏ - Wiley Online Library
Abstract Peroxynitrite (ONOO−), the reaction product derived from nitric oxide (NO) and
superoxide (O2−•), is a potent oxidizing and nitrating agent that modulates complex …