The Ebola outbreak, 2013–2016: old lessons for new epidemics

CEM Coltart, B Lindsey, I Ghinai… - … of the Royal …, 2017 - royalsocietypublishing.org
Ebola virus causes a severe haemorrhagic fever in humans with high case fatality and
significant epidemic potential. The 2013–2016 outbreak in West Africa was unprecedented …

The evolution of Ebola virus: Insights from the 2013–2016 epidemic

EC Holmes, G Dudas, A Rambaut, KG Andersen - Nature, 2016 - nature.com
The 2013–2016 epidemic of Ebola virus disease in West Africa was of unprecedented
magnitude and changed our perspective on this lethal but sporadically emerging virus. This …

Outbreak. info genomic reports: scalable and dynamic surveillance of SARS-CoV-2 variants and mutations

K Gangavarapu, AA Latif, JL Mullen, M Alkuzweny… - Nature …, 2023 - nature.com
In response to the emergence of SARS-CoV-2 variants of concern, the global scientific
community, through unprecedented effort, has sequenced and shared over 11 million …

Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events

JE Lemieux, KJ Siddle, BM Shaw, C Loreth… - Science, 2021 - science.org
INTRODUCTION We used genomic epidemiology to investigate the introduction and spread
of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the Boston area …

Centrifuge: rapid and sensitive classification of metagenomic sequences

D Kim, L Song, FP Breitwieser, SL Salzberg - Genome research, 2016 - genome.cshlp.org
Centrifuge is a novel microbial classification engine that enables rapid, accurate, and
sensitive labeling of reads and quantification of species on desktop computers. The system …

Real-time, portable genome sequencing for Ebola surveillance

J Quick, NJ Loman, S Duraffour, JT Simpson, E Severi… - Nature, 2016 - nature.com
The Ebola virus disease epidemic in West Africa is the largest on record, responsible for
over 28,599 cases and more than 11,299 deaths. Genome sequencing in viral outbreaks is …

A SARS-CoV-2 vaccine candidate would likely match all currently circulating variants

B Dearlove, E Lewitus, H Bai, Y Li… - Proceedings of the …, 2020 - National Acad Sciences
The magnitude of the COVID-19 pandemic underscores the urgency for a safe and effective
vaccine. Many vaccine candidates focus on the Spike protein, as it is targeted by …

Establishment and cryptic transmission of Zika virus in Brazil and the Americas

NR Faria, J Quick, IM Claro, J Theze, JG de Jesus… - Nature, 2017 - nature.com
Transmission of Zika virus (ZIKV) in the Americas was first confirmed in May 2015 in
northeast Brazil. Brazil has had the highest number of reported ZIKV cases worldwide (more …

[PDF][PDF] Genomic sequencing of SARS-CoV-2: a guide to implementation for maximum impact on public health, 8 January 2021

World Health Organization - 2021 - apps.who.int
The year 2020 was a turning point in history and in global health. The COVID-19 pandemic
has highlighted the potential for deadly epidemic-prone diseases to overwhelm our …

Virus genomes reveal factors that spread and sustained the Ebola epidemic

G Dudas, LM Carvalho, T Bedford, AJ Tatem, G Baele… - Nature, 2017 - nature.com
Abstract The 2013–2016 West African epidemic caused by the Ebola virus was of
unprecedented magnitude, duration and impact. Here we reconstruct the dispersal …