Genome walking is a method used to retrieve unknown flanking DNA. Here, we reported
wristwatch (WW) PCR, an efficient genome walking technique mediated by WW primers …

Approximately 70% of oropharyngeal squamous carcinomas (OPSCC) are associated with
human papillomavirus (HPV). Although patients with HPV-positive (HPV+) tumors generally …

Integration site (IS) analysis is essential in ensuring safety and efficacy of gene therapies
when integrating vectors are employed. Although clinical trials of gene therapy are rapidly …

Background Mobilization of transposable elements (TEs) can generate large effect
mutations. However, because new TE insertions are challenging to detect and transposition …

Cancer genome sequencing has identified dozens of mutations with a putative role in
lymphomagenesis and leukemogenesis. Validation of driver mutations responsible for B cell …

In spite of the enormous potential of CRISPR/Cas in basic and applied science, the levels of
undesired genomic modifications cells still remain mostly unknown and controversial …

Özet Bu çalışmada, tıbbi araştırmalarda ve moleküler biyoloji alanında kullanıma girmesi ile
bilimsel çalışmalara ivme kazandıran polimeraz zincir reaksiyonunun (PCR), teknolojik …

In spite of the enormous potential of CRISPR/Cas in basic and applied science, the levels of
undesired genomic modifications cells still remain mostly unknown and controversial …