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Applications, challenges, and needs for employing synthetic biology beyond the lab
Synthetic biology holds great promise for addressing global needs. However, most current
developments are not immediately translatable to 'outside-the-lab'scenarios that differ from …
developments are not immediately translatable to 'outside-the-lab'scenarios that differ from …
Applications of synthetic biology in medical and pharmaceutical fields
X Yan, X Liu, C Zhao, GQ Chen - Signal transduction and targeted …, 2023 - nature.com
Synthetic biology aims to design or assemble existing bioparts or bio-components for useful
bioproperties. During the past decades, progresses have been made to build delicate …
bioproperties. During the past decades, progresses have been made to build delicate …
Progress in biopharmaceutical development
M Kesik‐Brodacka - Biotechnology and applied biochemistry, 2018 - Wiley Online Library
Since its introduction in 1982, biopharmaceutical drugs have revolutionized the treatment of
a broad spectrum of diseases and are increasingly used in nearly all branches of medicine …
a broad spectrum of diseases and are increasingly used in nearly all branches of medicine …
Exploring the potential of cell-free protein synthesis for extending the abilities of biological systems
Cell-free protein synthesis (CFPS) system is a simple, rapid, and sensitive tool that is devoid
of membrane-bound barriers, yet contains all the mandatory substrates, biomolecules, and …
of membrane-bound barriers, yet contains all the mandatory substrates, biomolecules, and …
Synthetic biology and metabolic engineering of actinomycetes for natural product discovery
Actinomycetes are one of the most valuable sources of natural products with industrial and
medicinal importance. After more than half a century of exploitation, it has become …
medicinal importance. After more than half a century of exploitation, it has become …
Synthetic biology goes cell-free
A Tinafar, K Jaenes, K Pardee - BMC biology, 2019 - Springer
Cell-free systems (CFS) have recently evolved into key platforms for synthetic biology
applications. Many synthetic biology tools have traditionally relied on cell-based systems …
applications. Many synthetic biology tools have traditionally relied on cell-based systems …
Cell-free protein synthesis: a promising option for future drug development
SK Dondapati, M Stech, A Zemella, S Kubick - BioDrugs, 2020 - Springer
Proteins are the main source of drug targets and some of them possess therapeutic potential
themselves. Among them, membrane proteins constitute approximately 50% of the major …
themselves. Among them, membrane proteins constitute approximately 50% of the major …
Programming mammalian cell behaviors by physical cues
In recent decades, the field of synthetic biology has witnessed remarkable progress, driving
advances in both research and practical applications. One pivotal area of development …
advances in both research and practical applications. One pivotal area of development …
Compartmentalizing cell-free systems: toward creating life-like artificial cells and beyond
Building an artificial cell is a research area that is rigorously studied in the field of synthetic
biology. It has brought about much attention with the aim of ultimately constructing a natural …
biology. It has brought about much attention with the aim of ultimately constructing a natural …
Protein mediated enzyme immobilization
Enzyme immobilization is an essential technology for commercializing biocatalysis. It
imparts stability, recoverability, and other valuable features that improve the effectiveness of …
imparts stability, recoverability, and other valuable features that improve the effectiveness of …