Doxorubicin is an effective chemotherapeutic agent prescribed to treat solid tumors (eg,
ovary, breast, and gastrointestinal cancers). This anti-cancer drug has various side effects …

Today the pharmacological possibilities of treating cancer are expanding and as a result, life
expectancy is increasing against the background of chemotherapy and supportive treatment …

Doxorubicin (DOX) is an effective antineoplastic agent used to treat various types of cancers.
However, its use is limited by the development of cardiotoxicity, which may result in heart …

The study of mechanisms underlying cardiotoxicity of doxorubicin and the development of
strategies to mitigate doxorubicin-induced cardiotoxicity are the most relevant issues of …

According to the World Health Organization, the neoplasm is one of the main reasons for
morbidity and mortality worldwide. At the same time, application of cytostatic drugs like an …

Vincristine is an effective anticancer agent for treating leukemias, lymphomas, and other
solid tumors. Vincristine's better-known severe side effects include bone marrow depression …

Doxorubicin (DOXO) induces marked cardiotoxicity, though increased oxidative stress while
there are some documents related with cardioprotective effects of some antioxidants against …

Doxorubicin (DOX), a cornerstone chemotherapeutic agent, effectively combats various
malignancies but is marred by significant cardiovascular toxicity, including endothelial …

Ostarine is the most popular compound in the selective androgen receptor modulator group
(SARMs). Ostarine is used as a physical performance-enhancing agent. The abuse of this …

Human epidermal growth factor receptor-2 (HER2) is overexpressed in up to 30% of breast
cancer cases, causing a more aggressive tumour growth and poor prognosis. Trastuzumab …