Recent developments in two-dimensional liquid chromatography: fundamental improvements for practical applications

BWJ Pirok, DR Stoll, PJ Schoenmakers - Analytical Chemistry, 2018 - ACS Publications
Liquid chromatography (LC) is an incredibly successful analytical separation tool. Its
versatility is unprecedented because of the many different separation modes …

Recent trends in preparation, investigation and application of polysaccharide-based chiral stationary phases for separation of enantiomers in high-performance liquid …

B Chankvetadze - TrAC Trends in Analytical Chemistry, 2020 - Elsevier
This review article summarizes the recent developments in preparation, investigation and
application of polysaccharide-based chiral stationary phases for the separation of …

Optimizing separations in online comprehensive two‐dimensional liquid chromatography

BWJ Pirok, AFG Gargano… - Journal of separation …, 2018 - Wiley Online Library
Online comprehensive two‐dimensional liquid chromatography has become an attractive
option for the analysis of complex nonvolatile samples found in various fields (eg …

Recent trends in chiral supercritical fluid chromatography

C West - TrAC Trends in Analytical Chemistry, 2019 - Elsevier
This paper presents a review of the recent literature covering separations of enantiomers
achieved with supercritical fluid chromatography (SFC) or subcritical fluid chromatography …

Recent advances in chromatography for pharmaceutical analysis

V D'Atri, S Fekete, A Clarke, JL Veuthey… - Analytical …, 2018 - ACS Publications
The pharmaceutical industry is one of the most regulated industries worldwide, since the
drug products have to be safe and effective. The levels of impurities and degradation …

[HTML][HTML] Metamorphosis of supercritical fluid chromatography: a viable tool for the analysis of polar compounds?

GL Losacco, JL Veuthey, D Guillarme - TrAC Trends in Analytical …, 2021 - Elsevier
Recent developments in supercritical fluid chromatography (SFC) have highlighted the
applicability of this technique for the analysis of highly polar compounds. The combination of …

Two-dimensional liquid chromatography in pharmaceutical analysis. Instrumental aspects, trends and applications

M Iguiniz, S Heinisch - Journal of Pharmaceutical and Biomedical Analysis, 2017 - Elsevier
The interest in two-dimensional liquid chromatography (2D-LC) has been growing up since
the last decades. This promising technique appears as a relevant solution for various …

Enantioselective UHPLC Screening Combined with In Silico Modeling for Streamlined Development of Ultrafast Enantiopurity Assays

GL Losacco, H Wang, IA Haidar Ahmad… - Analytical …, 2021 - ACS Publications
Enantioselective chromatography has been the preferred technique for the determination of
enantiomeric excess across academia and industry. Although sequential multicolumn …

High throughput analysis enables high throughput experimentation in pharmaceutical process research

CJ Welch - Reaction Chemistry & Engineering, 2019 - pubs.rsc.org
High throughput experimentation has become widely used in the discovery and
development of new medicines. Progress in the field relies on an interplay between high …

[HTML][HTML] Two-dimensional liquid chromatography with reversed phase in both dimensions: A review

AA Aly, T Górecki - Journal of Chromatography A, 2024 - Elsevier
Two-dimensional liquid chromatography (2D-LC), and in particular comprehensive two-
dimensional liquid chromatography (LC× LC), offers increased peak capacity, resolution and …