[PDF][PDF] Renal cell carcinoma: an overview of the epidemiology, diagnosis, and treatment
S Bahadoram, M Davoodi, S Hassanzadeh… - G Ital Nefrol, 2022 - researchgate.net
Renal cell carcinoma (RCC) is the most common type of urogenital cancer. It has a mortality
rate of 30-40% and is more commonly seen in men than women. In addition to gender, other …
rate of 30-40% and is more commonly seen in men than women. In addition to gender, other …
The immunology of renal cell carcinoma
CM Díaz-Montero, BI Rini, JH Finke - Nature Reviews Nephrology, 2020 - nature.com
Renal cell carcinoma (RCC) is the most common type of kidney cancer and comprises
several subtypes with unique characteristics. The most common subtype (~ 70% of cases) is …
several subtypes with unique characteristics. The most common subtype (~ 70% of cases) is …
Histopathologic and proteogenomic heterogeneity reveals features of clear cell renal cell carcinoma aggressiveness
Clear cell renal cell carcinomas (ccRCCs) represent∼ 75% of RCC cases and account for
most RCC-associated deaths. Inter-and intratumoral heterogeneity (ITH) results in varying …
most RCC-associated deaths. Inter-and intratumoral heterogeneity (ITH) results in varying …
[HTML][HTML] Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma
Immune checkpoint blockade (ICB) results in durable disease control in a subset of patients
with advanced renal cell carcinoma (RCC), but mechanisms driving resistance are poorly …
with advanced renal cell carcinoma (RCC), but mechanisms driving resistance are poorly …
[HTML][HTML] Vision transformer and explainable transfer learning models for auto detection of kidney cyst, stone and tumor from CT-radiography
Renal failure, a public health concern, and the scarcity of nephrologists around the globe
have necessitated the development of an AI-based system to auto-diagnose kidney …
have necessitated the development of an AI-based system to auto-diagnose kidney …
Prognostic and predictive biomarkers for immunotherapy in advanced renal cell carcinoma
M Rosellini, A Marchetti, V Mollica, A Rizzo… - Nature Reviews …, 2023 - nature.com
The therapeutic algorithm of renal cell carcinoma has been revolutionized by the approval of
immunotherapy agents by regulatory agencies. However, objective and durable responses …
immunotherapy agents by regulatory agencies. However, objective and durable responses …
The Cancer Genome Atlas of renal cell carcinoma: findings and clinical implications
WM Linehan, CJ Ricketts - Nature Reviews Urology, 2019 - nature.com
Abstract The Cancer Genome Atlas (TCGA) characterized the somatic genetic and genomic
alterations in renal cell carcinoma (RCC) encompassing the major RCC histological …
alterations in renal cell carcinoma (RCC) encompassing the major RCC histological …
The cancer genome atlas comprehensive molecular characterization of renal cell carcinoma
Renal cell carcinoma (RCC) is not a single disease, but several histologically defined
cancers with different genetic drivers, clinical courses, and therapeutic responses. The …
cancers with different genetic drivers, clinical courses, and therapeutic responses. The …
[HTML][HTML] Map** single-cell transcriptomes in the intra-tumoral and associated territories of kidney cancer
Tumor behavior is intricately dependent on the oncogenic properties of cancer cells and
their multi-cellular interactions. To understand these dependencies within the wider …
their multi-cellular interactions. To understand these dependencies within the wider …
Nivolumab, nivolumab–ipilimumab, and VEGFR-tyrosine kinase inhibitors as first-line treatment for metastatic clear-cell renal cell carcinoma (BIONIKK): a biomarker …
YA Vano, R Elaidi, M Bennamoun, C Chevreau… - The Lancet …, 2022 - thelancet.com
Background We previously reported a 35-gene expression classifier identifying four clear-
cell renal cell carcinoma groups (ccrcc1 to ccrcc4) with different tumour microenvironments …
cell renal cell carcinoma groups (ccrcc1 to ccrcc4) with different tumour microenvironments …