Researchers have worked for many decades to master the rules of biomolecular design that
would allow artificial biopolymer complexes to self-assemble and function similarly to the …

In analogy to split-protein systems, which rely on the appropriate fragmentation of protein
domains, split aptamers made of two or more short nucleic acid strands have emerged as …

GFP and its derivatives revolutionized the study of proteins. Spinach is a recently reported in
vitro–evolved RNA mimic of GFP, which as genetically encoded fusions makes possible live …

RNA origami is a framework for the modular design of nanoscaffolds that can be folded from
a single strand of RNA and used to organize molecular components with nanoscale …

Small molecules play a major role in the human body and as drugs, toxins, and chemicals.
Tools to detect and quantify them are therefore in high demand. This review will give an …

Nucleic acids play a central role in all domains of life, either as genetic blueprints or as
regulators of various biochemical pathways. The 826chemical makeup of ribonucleic acid …

As food-borne pathogens, Bacillus cereus not only produce toxins that contaminate food and
threaten human health, but also rely on spores to resist extreme environments. At present …

Aptamers are exciting smart molecular probes for specific recognition of disease biomarkers.
A number of strategies have been developed to convert target–aptamer binding into …

Abstract 17β-Estradiol (E2), the strongest of the three major physiological estrogens in
females, is an important factor in the female reproductive system. The abnormal level of E2 …

The RNA-based organisms from which modern life is thought to have descended would
have depended on an RNA polymerase ribozyme to copy functional RNA molecules …