Intracellular pathogens are known to manipulate host cell regulatory pathways to establish
an optimal environment for their growth and survival. Pathogens employ active mechanisms …

Pathogen-specific rewiring of host cell metabolism creates the metabolically adapted
microenvironment required for pathogen replication. Here, we investigated the mechanisms …

Plasmodium falciparum (Pf), the causative agent of malaria, has an iron–sulfur cluster–
containing class I fumarate hydratase (FH) that catalyzes the interconversion of fumarate to …

Malaria is the most serious tropical disease of humankind and a cause of much debilitation
and morbidity throughout the world especially in endemic areas like India and Africa. The …

The purine salvage pathway offers potential enzyme targets for novel antimalarial agents.
Blocking the pathway by which adenosine obtained from the host cell is converted to the …

The study of host AMP-activated protein kinase (AMPK) activation during Leishmania
infection imposes distinct types of techniques to measure protein expression and activation …