Quinoxaline, its derivatives and applications: A State of the Art review

JA Pereira, AM Pessoa, MNDS Cordeiro… - European Journal of …, 2015 - Elsevier
Quinoxaline derivatives are an important class of heterocycle compounds, where N replaces
some carbon atoms in the ring of naphthalene. Its molecular formula is C 8 H 6 N 2, formed …

Novel synthetic routes to prepare biologically active quinoxalines and their derivatives: A synthetic review for the last two decades

H Khatoon, E Abdulmalek - Molecules, 2021 - mdpi.com
Quinoxalines, a class of N-heterocyclic compounds, are important biological agents, and a
significant amount of research activity has been directed towards this class. They have …

Quinoxaline 1,4-di-N-Oxides: Biological Activities and Mechanisms of Actions

G Cheng, W Sa, C Cao, L Guo, H Hao, Z Liu… - Frontiers in …, 2016 - frontiersin.org
Quinoxaline 1, 4-di-N-oxides (QdNOs) have manifold biological properties, including
antimicrobial, antitumoral, antitrypanosomal and antiinflammatory/antioxidant activities …

Present status of quinoxaline motifs: Excellent pathfinders in therapeutic medicine

OO Ajani - European journal of medicinal chemistry, 2014 - Elsevier
Quinoxalines belong to a class of excellent heterocyclic scaffolds owing to their wide
biological properties and diverse therapeutic applications in medicinal research. They are …

A review on the synthesis and pharmacological activity of heterocyclic compounds

J Baranwal, S Kushwaha, S Singh… - Current Physical …, 2023 - ingentaconnect.com
Biologically active compounds play a very important role in our daily life. Almost all
biologically active compounds contain heteroatoms and among these, a major portion is …

Quinoxaline derivatives as a promising scaffold for breast cancer treatment

RRE Eldin, AA Al-Karmalawy, MH Alotaibi… - New Journal of …, 2022 - pubs.rsc.org
According to Global Cancer Statistics 2021, female breast cancer has exceeded lung cancer
as the most frequently diagnosed cancer. As a result of this widespread breast cancer, it is …

Electronic structure and quantum chemical analysis of the corrosion inhibition efficiency of quinoxalines

DM Mamand, TMK Anwer, HM Qadr - Journal of the Indian Chemical …, 2023 - Elsevier
A theoretical investigation of the corrosion inhibition effectiveness of 1-[4-acetyl-2-(4-
chlorophenyl) quinoxalin-1 (4H)-yl] acetone (Q1), 2-(4-(2-ethoxy-2-oxoethyl)-2-p …

Synthesis and antiplasmodial activity of betulinic acid and ursolic acid analogues

AM Innocente, GNS Silva, LN Cruz, MS Moraes… - Molecules, 2012 - mdpi.com
More than 40% of the World population is at risk of contracting malaria, which affects
primarily poor populations in tropical and subtropical areas. Antimalarial pharmacotherapy …

Quinoxaline 1, 4-dioxides: advances in chemistry and chemotherapeutic drug development

GI Buravchenko, AE Shchekotikhin - Pharmaceuticals, 2023 - mdpi.com
N-Oxides of heterocyclic compounds are the focus of medical chemistry due to their diverse
biological properties. The high reactivity and tendency to undergo various rearrangements …

[HTML][HTML] In vitro activity and mechanism of cell death induction of cyanomethyl vinyl ethers derivatives against Trypanosoma cruzi

CJ Bethencourt-Estrella, S Delgado-Hernández… - International Journal for …, 2023 - Elsevier
Chagas disease causes a problematic pathology that can lead to megacolon and heart
disease, and can even cause the death of the patient. Current therapies for this disease are …