Copper (Cu) is a redox-active metal ion essential for most aerobic organisms. Cu serves as
a catalytic and structural cofactor for enzymes that function in energy generation, iron …

Throughout evolution, all organisms have harnessed the redox properties of copper (Cu)
and iron (Fe) as a cofactor or structural determinant of proteins that perform critical functions …

Metal transporters are a central component in the interaction of algae with their environment.
They represent the first line of defense to cellular perturbations in metal concentration, and …

Plants have developed sophisticated mechanisms to tightly control the acquisition and
distribution of copper and iron in response to environmental fluctuations. Recent studies with …

Iron, copper, and zinc are all essential nutrients. The electron transfer properties of iron and
copper are fundamental to processes such as respiration and photosynthesis. Zinc forms the …

Abstract Background The copper (Cu) transporter (COPT/Ctr) gene family has an important
role in the maintenance of Cu homeostasis in different species. The rice COPT-type gene …

For successful colonization and further reproduction in host plants, pathogens need to
overcome the innate defenses of the plant. We demonstrate that a novel pathogenicity gene …

Copper plays an essential role in processes including signaling to the transcription and
protein trafficking machinery, oxidative phosphorylation, iron mobilization, neuropeptide …

Redox-active metal ions, Cu (I/II) and Fe (II/III), are essential biological molecules for the
normal functioning of the brain, including oxidative metabolism, synaptic plasticity …

High-affinity cellular copper uptake is mediated by the CTR (copper transporter) 1 family of
proteins. The highly homologous hCTR (human CTR) 2 protein has been identified, but its …