The potential role of ischaemia–reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and …

DB Kell, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

Biomechanical properties of red blood cells in health and disease towards microfluidics

G Tomaiuolo - Biomicrofluidics, 2014 - pubs.aip.org
Red blood cells (RBCs) possess a unique capacity for undergoing cellular deformation to
navigate across various human microcirculation vessels, enabling them to pass through …

Fabrication of bioinspired hydrogels: challenges and opportunities

H Fan, JP Gong - Macromolecules, 2020 - ACS Publications
Since the birth of synthetic hydrogel 60 years ago, hydrogels possessing various useful
properties and functions have been developed. The research directions of hydrogels have …

Persistent capillary rarefication in long COVID syndrome

I Osiaevi, A Schulze, G Evers, K Harmening, H Vink… - Angiogenesis, 2023 - Springer
Background Recent studies have highlighted Coronavirus disease 2019 (COVID-19) as a
multisystemic vascular disease. Up to 60% of the patients suffer from long-term sequelae …

Red cells' dynamic morphologies govern blood shear thinning under microcirculatory flow conditions

L Lanotte, J Mauer, S Mendez… - Proceedings of the …, 2016 - National Acad Sciences
Blood viscosity decreases with shear stress, a property essential for an efficient perfusion of
the vascular tree. Shear thinning is intimately related to the dynamics and mutual …

Red blood cells: The metamorphosis of a neglected carrier into the natural mothership for artificial nanocarriers

PM Glassman, ED Hood, LT Ferguson, Z Zhao… - Advanced drug delivery …, 2021 - Elsevier
Drug delivery research pursues many types of carriers including proteins and other
macromolecules, natural and synthetic polymeric structures, nanocarriers of diverse …

Association between red blood cell distribution width and mortality and severity among patients with COVID‐19: a systematic review and meta‐analysis

JJ Lee, SM Montazerin, A Jamil, U Jamil… - Journal of medical …, 2021 - Wiley Online Library
Emerging evidence has underscored the potential usefulness of red blood cell distribution
width (RDW) measurement in predicting the mortality and disease severity of COVID‐19 …

Recent advances in microfluidic techniques for single-cell biophysical characterization

Y Zheng, J Nguyen, Y Wei, Y Sun - Lab on a Chip, 2013 - pubs.rsc.org
Biophysical (mechanical and electrical) properties of living cells have been proven to play
important roles in the regulation of various biological activities at the molecular and cellular …

Advances in the measurement of red blood cell deformability: A brief review

J Kim, HY Lee, S Shin - Journal of Cellular Biotechnology, 2015 - content.iospress.com
Red blood cells (RBCs) exhibit a unique deformability, which enables them to change shape
reversibly in response to an external force. The deformability of RBCs allows them to flow in …

Multiscale modeling of blood flow: from single cells to blood rheology

DA Fedosov, H Noguchi, G Gompper - Biomechanics and modeling in …, 2014 - Springer
Mesoscale simulations of blood flow, where the red blood cells are described as deformable
closed shells with a membrane characterized by bending rigidity and stretching elasticity …