New advances in the pharmacology and toxicology of lithium: a neurobiologically oriented overview
Over the last six decades, lithium has been considered the gold standard treatment for the
long-term management of bipolar disorder due to its efficacy in preventing both manic and …
long-term management of bipolar disorder due to its efficacy in preventing both manic and …
The impact of adult neurogenesis on affective functions: of mice and men
In most mammals, new neurons are not only produced during embryogenesis but also after
birth. Soon after adult neurogenesis was discovered, the influence of recruiting new neurons …
birth. Soon after adult neurogenesis was discovered, the influence of recruiting new neurons …
Lithium orotate: A superior option for lithium therapy?
AG Pacholko, LK Bekar - Brain and behavior, 2021 - Wiley Online Library
Bipolar disorder (BD) poses a significant public health concern, with roughly one‐quarter of
sufferers attempting suicide. BD is characterized by manic and depressive mood cycles, the …
sufferers attempting suicide. BD is characterized by manic and depressive mood cycles, the …
Immunomodulatory effect of lithium treatment on in vitro model of neuroinflammation
Bipolar disorder (BD) is psychiatric disorder of not fully acknowledged pathophysiology.
Studies show the involvement of innate-immune system activation and inflammation in BD …
Studies show the involvement of innate-immune system activation and inflammation in BD …
Lithium treatment and human hippocampal neurogenesis
Lithium is a first-line treatment for bipolar disorder, where it acts as a mood-stabilizing agent.
Although its precise mechanism remains unclear, neuroimaging studies have shown that …
Although its precise mechanism remains unclear, neuroimaging studies have shown that …
Lithium effects on hippocampus volumes in patients with bipolar disorder
S Lucini-Paioni, L Squarcina, DA Cousins… - Journal of affective …, 2021 - Elsevier
Background Lithium is one of the most effective medications for bipolar disorder episode
prevention, but its mechanism of action is still largely unknown. The hippocampus is a …
prevention, but its mechanism of action is still largely unknown. The hippocampus is a …
Genetic susceptibility to nicotine addiction: Advances and shortcomings in our understanding of the CHRNA5/A3/B4 gene cluster contribution
R Icick, B Forget, I Cloëz-Tayarani, S Pons, U Maskos… - …, 2020 - Elsevier
Over the last decade, robust human genetic findings have been instrumental in elucidating
the heritable basis of nicotine addiction (NA). They highlight coding and synonymous …
the heritable basis of nicotine addiction (NA). They highlight coding and synonymous …
Differences of resting fMRI and cognitive function between drug-naive bipolar disorder and schizophrenia
J Liang, W Huang, H Guo, W Wu, X Li, C Xu, G **e… - BMC psychiatry, 2022 - Springer
Background: Bipolar disorder (BD) and schizophrenia (SC) have many similarities in clinical
manifestations. The acute phase of BD has psychotic symptoms, while SC also has …
manifestations. The acute phase of BD has psychotic symptoms, while SC also has …
[HTML][HTML] Determination of lithium concentration in capillary blood using volumetric dried blood spots
F Wikström, C Olsson, B Palm, N Roxhed… - … of Pharmaceutical and …, 2023 - Elsevier
Background Lithium is a cornerstone in the treatment of bipolar disorder and is considered
one of the most effective treatments in psychiatry at large. Lithium treatment requires …
one of the most effective treatments in psychiatry at large. Lithium treatment requires …
Posttranslational modifications & lithium's therapeutic effect—Potential biomarkers for clinical responses in psychiatric & neurodegenerative disorders
Several neurodegenerative diseases and neuropsychiatric disorders display aberrant
posttranslational modifications (PTMs) of one, or many, proteins. Lithium treatment has been …
posttranslational modifications (PTMs) of one, or many, proteins. Lithium treatment has been …