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Evolving a peptide: library platforms and diversification strategies
K Bozovičar, T Bratkovič - International journal of molecular sciences, 2019 - mdpi.com
Peptides are widely used in pharmaceutical industry as active pharmaceutical ingredients,
versatile tools in drug discovery, and for drug delivery. They find themselves at the …
versatile tools in drug discovery, and for drug delivery. They find themselves at the …
Single‐chain fragment variable produced by phage display technology: construction, selection, mutation, expression, and recent applications in food safety
L Li, S Wu, Y Si, H Li, X Yin… - Comprehensive Reviews in …, 2022 - Wiley Online Library
Immunoassays are reliable, efficient, and accurate methods for the analysis of small‐
molecule harmful substances (such as pesticides, veterinary drugs, and biological toxins) …
molecule harmful substances (such as pesticides, veterinary drugs, and biological toxins) …
Current technological improvements in enzymes toward their biotechnological applications
Enzymes from extremophiles are creating interest among researchers due to their unique
properties and the enormous power of catalysis at extreme conditions. Since community …
properties and the enormous power of catalysis at extreme conditions. Since community …
Cognizance of molecular methods for the generation of mutagenic phage display antibody libraries for affinity maturation
Antibodies leverage on their unique architecture to bind with an array of antigens. The
strength of interaction has a direct relation to the affinity of the antibodies towards the …
strength of interaction has a direct relation to the affinity of the antibodies towards the …
Insight into de-regulation of amino acid feedback inhibition: a focus on structure analysis method
Regulation of amino acid's biosynthetic pathway is of significant importance to maintain
homeostasis and cell functions. Amino acids regulate their biosynthetic pathway by end …
homeostasis and cell functions. Amino acids regulate their biosynthetic pathway by end …
Fitness selection of hyperfusogenic measles virus F proteins associated with neuropathogenic phenotypes
S Ikegame, T Hashiguchi, CT Hung, K Dobrindt… - Proceedings of the …, 2021 - pnas.org
Measles virus (MeV) is resurgent and caused> 200,000 deaths in 2019. MeV infection can
establish a chronic latent infection of the brain that can recrudesce months to years after …
establish a chronic latent infection of the brain that can recrudesce months to years after …
MAIVeSS: streamlined selection of antigenically matched, high-yield viruses for seasonal influenza vaccine production
Vaccines are the main pharmaceutical intervention used against the global public health
threat posed by influenza viruses. Timely selection of optimal seed viruses with matched …
threat posed by influenza viruses. Timely selection of optimal seed viruses with matched …
A Y161F hemagglutinin substitution increases thermostability and improves yields of 2009 H1N1 influenza A virus in cells
Vaccination is the primary strategy for influenza prevention and control. However, egg-
based vaccines, the predominant production platform, have several disadvantages …
based vaccines, the predominant production platform, have several disadvantages …
[HTML][HTML] Development of an Enhanced High-Yield Influenza Vaccine Backbone in Embryonated Chicken Eggs
Vaccination is an efficient approach to preventing influenza virus infections. Recently, we
developed influenza A and B virus vaccine backbones that increased the yield of several …
developed influenza A and B virus vaccine backbones that increased the yield of several …
Forty years of directed evolution and its continuously evolving technology toolbox: A review of the patent landscape
Z Iqbal, S Sadaf - Biotechnology and Bioengineering, 2022 - Wiley Online Library
Generating functional protein variants with novel or improved characteristics has been a
goal of the biotechnology industry and life sciences, for decades. Rational design and …
goal of the biotechnology industry and life sciences, for decades. Rational design and …