Microwave irradiation (MWI), as a unique, effective, sustainable, more economic, and
greener source of energy compared to conventional heating, is applied in different organic …

Among isatin-based heterocyclic, spirooxindoles are interesting synthetic molecules
because of their variety of pharmacological activities. There is a wide range of multi …

Abstract A series of 5-aryl-3-(4-oxo-2-phenylquinazolin-3 (4 H)-yl)-2-(pyridin-4-yl) thiazolidin-
4-ones were synthesized and evaluated for their antibacterial and antifungal activities …

Two series of spiro-oxindole dihydroquinazolinone derivatives have been designed and
synthesized using a catalytic amount of nano cerium oxide with excellent product yields by a …

In this study, a series of 48 hybrids of the functionalised 1-[(1H-1, 2, 3-triazole-4-yl) methyl]
quinazoline-2, 4-dione 17–22 were synthesised and evaluated for potential antiviral activity …

The simple reaction approach has been designed and utilized for the synthesis of
quinazolinone benzamides 4a-4h using isatoic anhydride, m-Anisic hydrazide and various …

A facile and efficient one-pot procedure for the preparation of spirooxindole
dihydroquinazolinone derivatives and new N-(4-oxo-2-phenyl-1, 2-dihydroquinazolin-3 (4 …

The synthesis of 2-aminoquinazoline derivatives is achieved by using hydrochloric acid as a
mediator in the [4+ 2] annulation reaction between N-benzyl cyanamides and 2-amino aryl …

Coixspirolactams, spiro [oxindole-γ-lactones], are found in adlay seeds and exhibit
anticancer activity. A novel synthetic methodology was developed to enable an easy access …

Objective (s): Hybridization of bioactive natural and synthetic compounds is one of the most
promising novel approaches for the design of hit and lead compounds with new molecular …