Investigations over the past two decades are revealing complexities in the regulation of the
innate immune response, and how this response, in turn, controls adaptive immunity …

Changes in T cell trafficking accompany the naive to memory T cell antigen-driven
differentiation, which remains an incompletely defined developmental step. Upon priming …

Candida albicans is the most common human fungal pathogen causing mucosal and
systemic infections. However, human antifungal immunity remains poorly defined. Here by …

Influenza A virus (IAV) infection during pregnancy disrupts maternal and fetal health through
biological mechanisms, which are to date poorly characterised. During pregnancy, the viral …

Система интерферона (ИФН) играет одну из центральных ролей в иммунорегуляции,
включает механизмы врожденного и адаптивного иммунного ответа, является первой …

The bone marrow (BM) is an important site for the interrelated processes of hematopoiesis,
granulopoiesis, erythropoiesis, and lymphopoiesis. A wide variety of microbial challenges …

A fundamental challenge in immunology is to decipher the principles governing immune
responses at the whole-organism scale. Here, using a comparative infection model, we …

RNAi is considered a major antiviral defense mechanism in insects, but its relative
importance as compared to other antiviral pathways has not been evaluated …

Respiratory syncytial virus (RSV) causes mild to severe respiratory illness in humans and is
a major cause of hospitalizations of infants and the elderly. Both the innate and the adaptive …

Innate-like B-1a lymphocytes rapidly redistribute to regional mediastinal lymph nodes
(MedLNs) during influenza infection to generate protective IgM. Here we demonstrate that …