Medium N‐heterocycles, azepines and azocines, serve as important skeletons that occurred
widely in natural products, however, due to the lack of efficient synthetic methodologies, their …

Multiple C− H bond functionalizations promptly install diverse groups on the molecular
framework and consequently fabricate complex molecular entities. This review briefly …

An efficient Rh (III)-catalyzed selective mono-and dual-C–H bond functionalization/
cyclization with iodonium ylide as a single coupling partner was demonstrated, in which …

A silver-catalysed oxidative sp2 C–H alkylation of N-heteroarenes with ketone-derived 2, 3-
dihydroquinazolinones at room temperature is developed. The combination of a metal …

Herein, we demonstrated the oxidative cross-dehydrogenative coupling between amidines
and chalcones catalyzed by flavin and iodine. The riboflavin-iodine catalytic system played …

A concise synthesis of trifluoromethyl (CF3)-substituted azafluorenes based on the reaction
of 5-aryl-2 H-imidazoles with CF3-ynones is reported. The reaction proceeds through C–H …

The redox-neutral Ir (III)-or Ru (II)-catalyzed C–H couplings of azomethine imines with α, α-
difluoromethylene alkynes have been realized, leading to the efficient synthesis of …

An unprecedented route for the preparation of fused tetracyclic N-heterocycles is presented
through the palladium-catalyzed cyclization of isocyanides with alkyne-tethered aryl iodides …

By using weakly coordinating amines, we developed remote C–H alkynylation with precise
control of reactivity and regioselectivity, enabling modification of complex drugs, natural …

Haloalkynes that could be accessed from diverse precursors, are versatile in synthetic
chemistry as alkynylation and/or halogenation reagents, enabling concise and divergent …