Pfam, available via servers in the UK (http://pfam. sanger. ac. uk/) and the USA (http://pfam.
janelia. org/), is a widely used database of protein families, containing 14 831 manually …

The expansion of gene families encoding regulatory proteins is typically associated with the
increase in complexity characteristic of multi‐cellular organisms. The MYB and basic helix …

Sequence logos are visually compelling ways of illustrating the biological properties of DNA,
RNA and protein sequences, yet it is currently difficult to generate and customize such logos …

Pfam is a widely used database of protein families and domains. This article describes a set
of major updates that we have implemented in the latest release (version 24.0). The most …

Ecto-nucleotidases play a pivotal role in purinergic signal transmission. They hydrolyze
extracellular nucleotides and thus can control their availability at purinergic P2 receptors …

The WD40 domain exhibits a β-propeller architecture, often comprising seven blades. The
WD40 domain is one of the most abundant domains and also among the top interacting …

Pfam is a database of protein families that currently contains 7973 entries (release 18.0). A
recent development in Pfam has enabled the grou** of related families into clans. Pfam …

Background Logos are commonly used in molecular biology to provide a compact graphical
representation of the conservation pattern of a set of sequences. They render the information …

Recent findings indicate that WD40 domains play central roles in biological processes by
acting as hubs in cellular networks; however, they have been studied less intensely than …

Basic helix-loop-helix (bHLH) proteins are a class of transcription factors found throughout
eukaryotic organisms. Classification of the complete sets of bHLH proteins in the sequenced …