Multiple signaling pathways in Sertoli cells: recent findings in spermatogenesis

FD Ni, SL Hao, WX Yang - Cell death & disease, 2019 - nature.com
The functions of Sertoli cells in spermatogenesis have attracted much more attention
recently. Normal spermatogenesis depends on Sertoli cells, mainly due to their influence on …

The latest advances in the reproductive toxicity of microcystin-LR

S Zhang, X Du, H Liu, MD Losiewic, X Chen, Y Ma… - Environmental …, 2021 - Elsevier
Abstract Microcystin-LR (MC-LR) is an emerging environmental pollutant produced by
cyanobacteria that poses a threat to wild life and human health. In recent years, the …

A comprehensive review on potential role of selenium, selenoproteins and selenium nanoparticles in male fertility

S Yuan, Y Zhang, PY Dong, YMC Yan, J Liu, BQ Zhang… - Heliyon, 2024 - cell.com
Selenium (Se), a component of selenoproteins and selenocompounds in the human body, is
crucial for the development of male reproductive organs, DNA synthesis, thyroid hormone …

Immunotoxic effects induced by microcystins and cylindrospermopsin: A review

L Diez-Quijada, MM Benítez-González, M Puerto, A Jos… - Toxins, 2021 - mdpi.com
Cyanotoxin occurrence is gaining importance due to anthropogenic activities, climate
change and eutrophication. Among them, Microcystins (MCs) and Cylindrospermopsin …

The ameliorative effect of melatonin on LPS-induced Sertoli cells inflammatory and tight junctions damage via suppression of the TLR4/MyD88/NF-κB signaling …

R Feng, SO Adeniran, F Huang, Y Li, M Ma, P Zheng… - Theriogenology, 2022 - Elsevier
The blood-testicular barrier (BTB) is involved in spermatogenesis, protects sperm
development, and plays a crucial role in the reproductive process. Tight junctions (TJs) …

Waterborne microcystin-LR exposure induced chronic inflammatory response via MyD88-dependent toll-like receptor signaling pathway in male zebrafish

W Lin, H Guo, L Wang, D Zhang, X Wu, L Li… - Science of the total …, 2020 - Elsevier
Abstract Waterborne microcystin-LR (MC-LR) released by cyanobacterial blooms in
eutrophic water bodies have caused serious risk to aquatic animal and human health. In the …

[HTML][HTML] Bta-miR-149–3p suppresses inflammatory response in bovine Sertoli cells exposed to microcystin-leucine arginine (MC-LR) through TLR4/NF-kB signaling …

W Xue, W Tianrun, Y Jiaqi, L **n, D Ruxue… - … and Environmental Safety, 2024 - Elsevier
This study explored the regulatory role of bta-miR-149–3p in the inflammatory response
induced by microcystin-leucine arginine (MC-LR) exposure in bovine Sertoli cells. The …

Blood-brain barrier disruption and inflammation reaction in mice after chronic exposure to Microcystin-LR

J Wang, C Zhang, J Zhu, J Ding, Y Chen… - Science of the Total …, 2019 - Elsevier
Abstract Microcystin-leucine-arginine (MC-LR), which produced by toxic cyanobacteria and
widely present in eutrophic waters, has been shown to have potent acute hepatotoxicity. MC …

Parental transfer of microcystin-LR-induced innate immune dysfunction of zebrafish: a cross-generational study

W Lin, H Guo, L Wang, D Zhang, X Wu… - … science & technology, 2019 - ACS Publications
Transgenerational effects of microcystin-LR (MC-LR) released by cyanobacterial blooms
have become a hot topic. In the present study, adult zebrafish pairs were exposed to 0, 0.4 …

Long-term crowding stress induces chronic inflammatory response and declines the immunity of grass carp (Ctenopharyngodon idella)

W Li, D Li, Q Yang, L Liu, J Liu, J Lu, Y Wang, R Tang… - Aquaculture, 2023 - Elsevier
This study is aimed to explore the mechanism of overcrowding stress on the immunity of
grass carp Ctenopharyngodon idella. Fish were reared for 120 days at 10 kg/m 3 (low …