Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …
A review of hydrogen sulfide synthesis, metabolism, and measurement: is modulation of hydrogen sulfide a novel therapeutic for cancer?
Abstract Significance: Hydrogen sulfide (H2S) has been recognized as the third gaseous
transmitter alongside nitric oxide and carbon monoxide. In the past decade, numerous …
transmitter alongside nitric oxide and carbon monoxide. In the past decade, numerous …
The first 1000 cultured species of the human gastrointestinal microbiota
The microorganisms that inhabit the human gastrointestinal tract comprise a complex
ecosystem with functions that significantly contribute to our systemic metabolism and have …
ecosystem with functions that significantly contribute to our systemic metabolism and have …
Nutrients, foods, and colorectal cancer prevention
Diet has an important role in the development of colorectal cancer. In the past few decades,
findings from extensive epidemiologic and experimental investigations have linked …
findings from extensive epidemiologic and experimental investigations have linked …
Physiological implications of hydrogen sulfide: a whiff exploration that blossomed
R Wang - Physiological reviews, 2012 - journals.physiology.org
The important life-supporting role of hydrogen sulfide (H2S) has evolved from bacteria to
plants, invertebrates, vertebrates, and finally to mammals. Over the centuries, however, H2S …
plants, invertebrates, vertebrates, and finally to mammals. Over the centuries, however, H2S …
Tumor-derived hydrogen sulfide, produced by cystathionine-β-synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer
The physiological functions of hydrogen sulfide (H2S) include vasorelaxation, stimulation of
cellular bioenergetics, and promotion of angiogenesis. Analysis of human colon cancer …
cellular bioenergetics, and promotion of angiogenesis. Analysis of human colon cancer …
Relevance of protein fermentation to gut health
K Windey, V De Preter… - Molecular nutrition & food …, 2012 - Wiley Online Library
It is generally accepted that carbohydrate fermentation results in beneficial effects for the
host because of the generation of short chain fatty acids, whereas protein fermentation is …
host because of the generation of short chain fatty acids, whereas protein fermentation is …
Towards microbial fermentation metabolites as markers for health benefits of prebiotics
Available evidence on the bioactive, nutritional and putative detrimental properties of gut
microbial metabolites has been evaluated to support a more integrated view of how …
microbial metabolites has been evaluated to support a more integrated view of how …
Bile salt biotransformations by human intestinal bacteria
JM Ridlon, DJ Kang, PB Hylemon - Journal of lipid research, 2006 - ASBMB
Secondary bile acids, produced solely by intestinal bacteria, can accumulate to high levels
in the enterohepatic circulation of some individuals and may contribute to the pathogenesis …
in the enterohepatic circulation of some individuals and may contribute to the pathogenesis …
Taurocholic acid metabolism by gut microbes and colon cancer
Colorectal cancer (CRC) is one of the most frequent causes of cancer death worldwide and
is associated with adoption of a diet high in animal protein and saturated fat. Saturated fat …
is associated with adoption of a diet high in animal protein and saturated fat. Saturated fat …