Aptamers are single-stranded nucleic acids that selectively bind to target molecules. Most
aptamers are obtained through a combinatorial biology technique called SELEX. Since …

When a molecule absorbs a photon of appropriate energy, a chain of photophysical events
ensues, such as internal conversion or vibrational relaxation (loss of energy in the absence …

In vivo medical imaging has made great progress due to advances in the engineering of
imaging devices and developments in the chemistry of imaging probes. Several modalities …

Sensors are devices that respond to physical or chemical stimuli and produce detectable
signals. 1r4 They are a critical extension of human perception of the world in many aspects …

Nucleic acids hold promise as biomolecules for future applications in biomedicine and
biotechnology. Their well-defined structures and compositions afford unique chemical …

Nanomaterial-based field-effect transistor (FET) sensors are capable of label-free real-time
chemical and biological detection with high sensitivity and spatial resolution, although direct …

Portable, low-cost and quantitative detection of a broad range of targets at home and in the
field has the potential to revolutionize medical diagnostics and environmental monitoring …

Nucleic-acid aptamers have attracted intense interest and found wide applications in a
range of areas. In this review, we summarize recent advances in the development of …

Using cell-based aptamer selection, we have developed a strategy to use the differences at
the molecular level between any two types of cells for the identification of molecular …

Nucleic acid aptamers are single stranded DNA or RNA sequences that specifically bind a
cognate ligand. In addition to their widespread use as stand-alone affinity binding reagents …