Gut-liver axis: Pathophysiological concepts and clinical implications
H Tilg, TE Adolph, M Trauner - Cell metabolism, 2022 - cell.com
Bidirectional crosstalk along the gut-liver axis controls gastrointestinal health and disease
and exploits environmental and host mediators. Nutrients, microbial antigens, metabolites …
and exploits environmental and host mediators. Nutrients, microbial antigens, metabolites …
Role of bile acids and their receptors in gastrointestinal and hepatic pathophysiology
CD Fuchs, M Trauner - Nature reviews Gastroenterology & hepatology, 2022 - nature.com
Bile acids (BAs) can regulate their own metabolism and transport as well as other key
aspects of metabolic homeostasis via dedicated (nuclear and G protein-coupled) receptors …
aspects of metabolic homeostasis via dedicated (nuclear and G protein-coupled) receptors …
EASL Clinical Practice Guidelines on sclerosing cholangitis
Management of primary or secondary sclerosing cholangitis is challenging. These Clinical
Practice Guidelines have been developed to provide practical guidance on debated topics …
Practice Guidelines have been developed to provide practical guidance on debated topics …
Pathophysiological mechanisms of liver injury in COVID‐19
AD Nardo, M Schneeweiss‐Gleixner… - Liver …, 2021 - Wiley Online Library
The recent outbreak of coronavirus disease 2019 (COVID‐19), caused by the Severe Acute
Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2) has resulted in a world‐wide …
Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2) has resulted in a world‐wide …
Molecular physiology of bile acid signaling in health, disease, and aging
A Perino, H Demagny… - Physiological …, 2021 - journals.physiology.org
Over the past two decades, bile acids (BAs) have become established as important
signaling molecules that enable fine-tuned inter-tissue communication from the liver, their …
signaling molecules that enable fine-tuned inter-tissue communication from the liver, their …
[PDF][PDF] Primary biliary cholangitis: 2018 practice guidance from the American Association for the Study of Liver Diseases
KD Lindor, CL Bowlus, J Boyer, C Levy, M Mayo - Hepatology, 2019 - Wiley Online Library
This American Association for the Study of Liver Diseases (AASLD) 2018 Practice Guidance
on Primary Biliary Cholangitis (PBC) is an update of the PBC guidelines published in 2009 …
on Primary Biliary Cholangitis (PBC) is an update of the PBC guidelines published in 2009 …
Bile acid–microbiota crosstalk in gastrointestinal inflammation and carcinogenesis
Emerging evidence points to a strong association between the gut microbiota and the risk,
development and progression of gastrointestinal cancers such as colorectal cancer (CRC) …
development and progression of gastrointestinal cancers such as colorectal cancer (CRC) …
Primary biliary cholangitis
Primary biliary cholangitis is an autoimmune liver disease that predominantly affects women.
It is characterised by a chronic and destructive, small bile duct, granulomatous lymphocytic …
It is characterised by a chronic and destructive, small bile duct, granulomatous lymphocytic …
Novel therapeutic targets for cholestatic and fatty liver disease
M Trauner, CD Fuchs - Gut, 2022 - gut.bmj.com
Cholestatic and non-alcoholic fatty liver disease (NAFLD) share several key
pathophysiological mechanisms which can be targeted by novel therapeutic concepts that …
pathophysiological mechanisms which can be targeted by novel therapeutic concepts that …
EASL Clinical Practice Guidelines: The diagnosis and management of patients with primary biliary cholangitis
Primary biliary cholangitis (PBC) is a chronic inflammatory autoimmune cholestatic liver
disease, which when untreated will culminate in end-stage biliary cirrhosis. Diagnosis is …
disease, which when untreated will culminate in end-stage biliary cirrhosis. Diagnosis is …