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Lights, fiber, action! A primer on in vivo fiber photometry
Fiber photometry is a key technique for characterizing brain-behavior relationships in vivo.
Initially, it was primarily used to report calcium dynamics as a proxy for neural activity via …
Initially, it was primarily used to report calcium dynamics as a proxy for neural activity via …
Two-photon calcium imaging of neuronal activity
In vivo two-photon calcium imaging (2PCI) is a technique used for recording neuronal
activity in the intact brain. It is based on the principle that, when neurons fire action …
activity in the intact brain. It is based on the principle that, when neurons fire action …
Fluorescent proteins and genetically encoded biosensors
M Wang, Y Da, Y Tian - Chemical Society Reviews, 2023 - pubs.rsc.org
The genetically encoded fluorescent sensors convert chemical and physical signals into
light. They are powerful tools for the visualisation of physiological processes in living cells …
light. They are powerful tools for the visualisation of physiological processes in living cells …
Multifunctional materials for implantable and wearable photonic healthcare devices
Numerous light-based diagnostic and therapeutic devices are routinely used in the clinic.
These devices have a familiar look as items plugged in the wall or placed at patients' …
These devices have a familiar look as items plugged in the wall or placed at patients' …
A positively tuned voltage indicator for extended electrical recordings in the brain
Genetically encoded voltage indicators (GEVIs) enable optical recording of electrical signals
in the brain, providing subthreshold sensitivity and temporal resolution not possible with …
in the brain, providing subthreshold sensitivity and temporal resolution not possible with …
Focused ultrasound excites cortical neurons via mechanosensitive calcium accumulation and ion channel amplification
Ultrasonic neuromodulation has the unique potential to provide non-invasive control of
neural activity in deep brain regions with high spatial precision and without chemical or …
neural activity in deep brain regions with high spatial precision and without chemical or …
Genetically encoded fluorescent biosensors illuminate the spatiotemporal regulation of signaling networks
Cellular signaling networks are the foundation which determines the fate and function of
cells as they respond to various cues and stimuli. The discovery of fluorescent proteins over …
cells as they respond to various cues and stimuli. The discovery of fluorescent proteins over …
Dual-polarity voltage imaging of the concurrent dynamics of multiple neuron types
Genetically encoded fluorescent voltage indicators are ideally suited to reveal the
millisecond-scale interactions among and between targeted cell populations. However …
millisecond-scale interactions among and between targeted cell populations. However …
Bright and photostable chemigenetic indicators for extended in vivo voltage imaging
Genetically encoded voltage indicators (GEVIs) enable monitoring of neuronal activity at
high spatial and temporal resolution. However, the utility of existing GEVIs has been limited …
high spatial and temporal resolution. However, the utility of existing GEVIs has been limited …
[HTML][HTML] Ultrafast two-photon imaging of a high-gain voltage indicator in awake behaving mice
Optical interrogation of voltage in deep brain locations with cellular resolution would be
immensely useful for understanding how neuronal circuits process information. Here, we …
immensely useful for understanding how neuronal circuits process information. Here, we …