Synthetic product-based approach toward potential antileishmanial drug development
Leishmaniasis is a parasitic disease and is categorized as a tropically neglected disease
(NTD) with no effective vaccines available. The available chemotherapeutics against …
(NTD) with no effective vaccines available. The available chemotherapeutics against …
Mexican Oregano (Lippia graveolens Kunth) as Source of Bioactive Compounds: A Review
Lippia graveolens is a traditional crop and a rich source of bioactive compounds with
various properties (eg, antioxidant, anti-inflammatory, antifungal, UV defense, anti-glycemic …
various properties (eg, antioxidant, anti-inflammatory, antifungal, UV defense, anti-glycemic …
The role of natural anti-parasitic guided development of synthetic drugs for leishmaniasis
Leishmaniasis is a parasitic disease and categorised as a neglected tropical disease (NTD).
Each year, between 70, 0000 and 1 million new cases are believed to occur. There are …
Each year, between 70, 0000 and 1 million new cases are believed to occur. There are …
The ambiguous role of mannose-binding lectin (MBL) in human immunity
Mannose-binding lectin (MBL) and lectin complement pathway have become targets of
increasing clinical interest. Many aspects of MBL have been recently explored, including the …
increasing clinical interest. Many aspects of MBL have been recently explored, including the …
An appraisal of the scientific current situation and new perspectives in the treatment of cutaneous leishmaniasis
CAB Nieva, AG Cid, AI Romero, MF García-Bustos… - Acta Tropica, 2021 - Elsevier
Abstract Leishmaniasis is a Neglected Tropical Diseases caused by protozoan parasites of
the genus Leishmania. It is a major health problem in many tropical and subtropical regions …
the genus Leishmania. It is a major health problem in many tropical and subtropical regions …
[HTML][HTML] Synthesis, spectroscopic characterization, antileishmanial, DNA binding, antioxidant, cytotoxicity, antifungal and antibacterial studies of organotin (IV) …
S Hussain, S Shujah, A Rehman, ST Hussain… - Arabian Journal of …, 2023 - Elsevier
Six new organotin (IV) complexes,[Bu 2 SnL](1),[Me 2 SnL](2),[Me 3 SnL](3),[Bu 3
SnL](4),[Ph 3 SnL](5) and [(n-Oct 2 SnL](6) have been synthesized from the reaction of 4-((5 …
SnL](4),[Ph 3 SnL](5) and [(n-Oct 2 SnL](6) have been synthesized from the reaction of 4-((5 …
Modeling and simulation study to identify threonine synthase as possible drug target in Leishmania major
Leishmaniasis is one of the most neglected tropical diseases that demand immediate
attention to the identification of new drug targets and effective drug candidates. The present …
attention to the identification of new drug targets and effective drug candidates. The present …
C57BL/6 Peritoneal Macrophage Exosomes Improve Antileishmanial Functions of the RAW264. 7 Cells
H Gandomkar, M Changaei, MM Hosseini… - Parasite …, 2024 - Wiley Online Library
Leishmaniasis is considered one of the most critical health concerns in the world.
Unfortunately, no protective vaccines exist and conventional treatments are relatively …
Unfortunately, no protective vaccines exist and conventional treatments are relatively …
Identification of Novel Antileishmanial Chemotypes By High-Throughput Virtual and In Vitro Screening
Background Leishmaniasis is a deadly protozoan parasitic disease and a significant health
problem in underdeveloped and develo** countries. The global spread of the parasite …
problem in underdeveloped and develo** countries. The global spread of the parasite …
Annonaceae family alkaloids as agents against Leishmaniasis: a review and molecular docking evaluation
Leishmaniasis is a neglected disease that affects 15 million people worldwide. Existing
treatments are associated with limitations, including high costs and toxicity. Several classes …
treatments are associated with limitations, including high costs and toxicity. Several classes …