Atherosclerosis (AS) is the major form of cardiovascular disease and the leading cause of
morbidity and mortality in countries around the world. Atherosclerosis combines the …

The leading cause of heart disease in developed countries is coronary atherosclerosis,
which is not simply a result of ageing but a chronic inflammatory process that can lead to …

Although arterial and venous thromboembolic disorders are among the most frequent
causes of mortality and morbidity, there has been little description of how the composition of …

Advanced drug delivery systems (DDS) enhance treatment efficacy of different therapeutics
in a dosage, spatial, and/or temporal controlled manner. To date, numerous chemical-or …

Background Experimental studies suggest that low wall shear stress (WSS) promotes
plaque development and high WSS is associated with plaque destabilization. We …

Obstruction of critical blood vessels due to thrombosis or embolism is a leading cause of
death worldwide. Here, we describe a biomimetic strategy that uses high shear stress …

Acute arterial occlusions occur in high shear rate hemodynamic conditions. Arterial thrombi
are platelet-rich when examined histologically compared with red blood cells in venous …

Virchow's triad is traditionally invoked to explain pathophysiologic mechanisms leading to
thrombosis, alleging concerted roles for abnormalities in blood composition, vessel wall …

The targeted delivery to specific locations while not causing damage to healthy tissues
efficiently remains a challenge in drug delivery systems. Through addressing this issue …

Ischemic stroke is a vascular central nervous system (CNS) disease that leads a disability
and death. Thrombolysis and neuroprotection are the primary treatment strategies of …