New potent immunomodulatory therapies for multiple sclerosis (MS) are associated with
increased risk for progressive multifocal leukoencephalopathy (PML). It is unclear why a …

Latent infection with cytomegalovirus (CMV) is thought to accelerate aging of the immune
system. With age, influenza vaccine responses are impaired. Although several studies …

Certain infectious agents are recognised causes of cancer and other chronic diseases. To
understand the pathological mechanisms underlying such relationships, here we design a …

Cytometry technologies are essential tools for immunology research, providing high-
throughput measurements of the immune cells at the single-cell level. Existing approaches …

Cytomegalovirus (CMV) infection has a major impact on the T-cell pool, which is thought to
be associated with ageing of the immune system. The effect on the T-cell pool has been …

Despite decades of research, human cytomegalovirus (CMV) continues to contribute to
significant morbidity and mortality in transplant settings and remains the leading cause of …

A vaccine to prevent congenital cytomegalovirus infection (cCMV) is a public health priority.
cCMV results from maternal primary or non-primary CMV infection (reinfection, or …

Objectives Cytomegalovirus infection is thought to affect the immune system and to impact
general health during ageing. Higher CMV‐specific antibody levels in the elderly are …

Evaluate risk factors for cytomegalovirus (CMV) reactivation during the first year after kidney
transplantation in the CMV-seropositive older recipient. Retrospective single-center study …

CD8+ T cells play an important role in protection against viral infections. With age, changes
in the T-cell pool occur, leading to diminished responses against both new and recurring …