Biomedical applications of quantum dots: overview, challenges, and clinical potential

AAH Abdellatif, MA Younis, M Alsharidah… - International journal …, 2022 - Taylor & Francis
Despite the massive advancements in the nanomedicines and their associated research,
their translation into clinically-applicable products is still below promises. The latter fact …

Small molecules as cancer targeting ligands: Shifting the paradigm

N Kaur, P Popli, N Tiwary, R Swami - Journal of Controlled Release, 2023 - Elsevier
Conventional chemotherapeutics exploration is hampered due to their nonspecific
distribution leading to unintended serious toxicity. Toxicity is so severe that deciding to go for …

Three-dimensional in vitro tumor spheroid models for evaluation of anticancer therapy: recent updates

P Nayak, V Bentivoglio, M Varani, A Signore - Cancers, 2023 - mdpi.com
Simple Summary Cancer is a global public health issue. The development and use of in vitro
cellular models with pre-clinical animal models are essential to elucidate the complex …

Application of nanoparticles in cancer treatment: a concise review

M Sell, AR Lopes, M Escudeiro, B Esteves… - Nanomaterials, 2023 - mdpi.com
Timely diagnosis and appropriate antitumoral treatments remain of utmost importance, since
cancer remains a leading cause of death worldwide. Within this context, nanotechnology …

Imaging cancer cells with nanostructures: Prospects of nanotechnology driven non-invasive cancer diagnosis

R Augustine, A Al Mamun, A Hasan, SA Salam… - Advances in Colloid and …, 2021 - Elsevier
The application of nanostructured materials in medicine is a rapidly evolving area of
research that includes both the diagnosis and treatment of various diseases. Metals, metal …

Quantum dots mediated imaging and phototherapy in cancer spheroid models: state of the art and perspectives

L Dirheimer, T Pons, F Marchal, L Bezdetnaya - Pharmaceutics, 2022 - mdpi.com
Quantum Dots (QDs) are fluorescent nanoparticles known for their exceptional optical
properties, ie, high fluorescence emission, photostability, narrow emission spectrum, and …

NIR imaging of the integrin-rich head and neck squamous cell carcinoma using ternary copper indium selenide/zinc sulfide-based quantum dots

I Yakavets, A Francois, M Guiot, N Lequeux, A Fragola… - Cancers, 2020 - mdpi.com
Simple Summary Despite improved patient outcomes in a range of cancers, the prognostic
of head and neck cancers remain poor, with more than 507,000 deaths annually. The …

Advances in the study of spheroids as versatile models to evaluate biological interactions of inorganic nanoparticles

RBL Henrique, RRM Lima, CAP Monteiro, WF Oliveira… - Life Sciences, 2022 - Elsevier
Spheroids are in vitro three-dimensional multicellular microstructures able to mimic the
biological microenvironment, including the complexity of tumor architecture. Therefore …

Cancer nanotechnology in medicine: a promising approach for cancer detection and diagnosis

BJ Stephen, S Suchanti, R Mishra… - Critical Reviews™ in …, 2020 - dl.begellhouse.com
Despite extraordinary advances that have been made in cancer therapy, the number of
cancer cases continue to surge, making it the leading cause of death across the world. As a …

Capture and detection of rare cancer cells in blood by intrinsic fluorescence of a novel functionalized diatom

J Esfandyari, B Shojaedin-Givi, H Hashemzadeh… - Photodiagnosis and …, 2020 - Elsevier
The ability to identify and enrich target cells can play a significant role in biosensing in
general. For the separation of rare cells; a biosilica structure was extracted from …